Results 81 to 90 of about 18,507,972 (283)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Which circulating antioxidant vitamins are confounded by socioeconomic deprivation? The MIDSPAN family study [PDF]

, 2010
<p><b>Background:</b> Antioxidant vitamins are often described as having “independent” associations with risk of cancer, cardiovascular disease (CVD) and mortality.
Welsh, P, Talwar Dinesh, Mark Upton, Davey Smith George, Watt, G., Sattar, N, Sattar, N., Talwar, D., Dinesh Talwar, O'Reilly Denis, Welsh Paul, Sattar Naveed, Paul Welsh, Davey Smith, G, O'Reilly, D, Graham Watt, Upton Mark, Upton, M, Alex McConnachie, McConnachie Alex, Welsh, P., McConnachie, A., Denis O'Reilly, Talwar, D, McConnachie, A, O'Reilly, D., Watt Graham, Naveed Sattar, Watt, G, Upton, M., George Davey Smith, Davey Smith, G.   +31 more
core   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Ascorbic Acid Levels in Vitamin Pills [PDF]

, 2010
Although it is generally accepted that a balanced diet without supplementation contains enough vitamin C, it is still the most widely taken nutritional supplement world-wide.
Özmen, İbrahim Asutay
core   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Cognitive and mood effects in healthy children during 12 weeks' supplementation with multi-vitamin/minerals [PDF]

, 2008
Adequate levels of vitamins and minerals are essential for optimal neural functioning. A high proportion of individuals, including children, suffer from deficiencies in one or more vitamins or minerals.
Kennedy, David O, Jackson, Philippa A, Robertson, Bernadette C, Defeyter, M.A., Greer, Joanna, Scholey, Andrew B, Jackson, Philippa, Jackson, P.A., Robertson, B.C., Buchanan, Tom, Scholey, Andrew, Haskell, Crystal F, Defeyter, Margaret Anne (Greta), Haskell, C.F., Kennedy, D.O., Scholey, A.B., Elliott, J.M., Tiplady, B., Defeyter, Margaret A, Haskell, Crystal, Kennedy, David, Elliott, Jade, Robertson, Bernadette, Buchanan, T., Tiplady, Brian, Greer, J., Elliott, Jade M   +26 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Vitamin A supplementation in Tanzania: the impact of a change in programmatic delivery strategy on coverage. [PDF]

, 2006
BACKGROUND\ud \ud Efficient delivery strategies for health interventions are essential for high and sustainable coverage. We report impact of a change in programmatic delivery strategy from routine delivery through the Expanded Programme on Immunization (
Honorati Masanja, de Savigny, Don, Masanja Honorati, Mshinda Hassan M, de Savigny Don, Joanna Armstrong Schellenberg, Meera Shekar, Masanja, Honorati, Schellenberg, Joanna Armstrong, Ndossi, Godwin D, Schellenberg Joanna, Mugyabuso Joseph KL, Ndossi Godwin D, Don de Savigny, Mshinda, Hassan M, Mugyabuso, Joseph KL, Hassan M Mshinda, Godwin D Ndossi, Shekar, Meera, Joseph KL Mugyabuso, Shekar Meera   +20 more
core   +2 more sources

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source