Results 111 to 120 of about 326,659 (304)

Vitamin D in combination with menopausal hormonal therapy in women. [PDF]

РМЖ. Мать и дитя
D.K. Muradova1, A.E. Esedova2, F.S. Mamedov2, T.S. Magomedova2 1LLC Center for Medicine and Diagnostics "My Doctor", Makhachkala, Russian Federation 2Dagestan State Medical University, Makhachkala, Russian Federation Background: A multitude ...
D.K. Muradova, A.E. Esedova, F.S. Mamedov, T.S. Magomedova   +3 more
doaj  

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

A 50-year-old female with dysuria, dysporia, numbness and weakness of extremities

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
This paper reports one patient, with a history of autoimmune gastritis, who presented dysuria and dysporia for 5 years, weakness of left upper limb for one and a half years, and numbness and weakness of extremities for 2 months.
Lin PENG, Wei-hai XU, Bin PENG, Li-ying CUI   +3 more
doaj  

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Functional Improvement in Geriatric Hip Fractures

Geriatric Orthopaedic Surgery & Rehabilitation, 2015
Introduction: The “Integrated Care Pathway” for geriatric intertrochanteric (IT) fractures in Singapore’s Tan Tock Seng Hospital has shown significant functional recovery in patients’ activities of daily living.
W. R. D. Seng MBChB, MRCS(Glasg), M. H. Belani, R. Ramason MBChB (Leeds), MRCP (UK), DGM (London), G. Naidu MBBS, FRCS (Edin), FRCS (Edin) (Ortho), FAMS (Ortho), H. K. Doshi Bac. Med. Sc, M.D. (M'sia), MRCS (Ed), AFRCSI (Dublin), FRCS Ed (Ortho), FEBOT (Europe), M.Med.Ortho (S'pore), Dip SICOT (Belgium)   +4 more
doaj   +1 more source

Intakes, adequacy, food sources and biomarker status of iron, folate, and vitamin B₁₂ in Māori and non-Māori octogenarians : life and living in advanced age : a cohort study in New Zealand (LiLACS NZ) : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Nutrition and Dietetics, Massey University, Albany, New Zealand [PDF]

, 2017
Background: Iron, folate and vitamin B12 are the three key nutrients associated with the development of anaemia and have also been associated with the dietary patterns linked to higher malnutrition risk in older adults.
Pillay, Danika
core  

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial^® Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial

Pharmaceutics
Background/Objectives: Vitamin B12 deficiency is common in individuals with type 2 diabetes mellitus (T2DM) receiving long-term metformin therapy, primarily due to impaired intestinal absorption.
Gabriele Conti, Allah W. Kalo, Ikram Ujjan, Aisha Aslam, Amjad Khan, Nazia M. Memon, Shair Z. Kakar, Naseer Ahmed, Shifa Zahid, Germano Tarantino, Elisa Brilli   +10 more
doaj   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source