Results 291 to 300 of about 794,897 (330)
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American Journal of Physiology-Renal Physiology, 1999
The vitamin D endocrine systems plays a critical role in calcium and phosphate homeostasis. The active form of vitamin D, 1,25-dihydroxyvitamin D3[1,25(OH)2D3], binds with high affinity to a specific cellular receptor that acts as a ligand-activated transcription factor.
Eduardo Slatopolsky +2 more
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The vitamin D endocrine systems plays a critical role in calcium and phosphate homeostasis. The active form of vitamin D, 1,25-dihydroxyvitamin D3[1,25(OH)2D3], binds with high affinity to a specific cellular receptor that acts as a ligand-activated transcription factor.
Eduardo Slatopolsky +2 more
openaire +4 more sources
Vitamin D and Vitamin D Dependency
2015Administration of large doses of vitamin D2 brought about a marked increase of 25-hydroxyvitamin D in both the patients with vitamin D dependency and hypophosphatemic vitamin D-resistant rickets. During the administration of vitamin D2, increment of 1,25-dihydroxyvitamin D was marked in hypophosphatemic vitamin D-resistant rickets, but far smaller in ...
Yutaka Tsuchiya +7 more
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The International Journal of Biochemistry & Cell Biology, 2009
The primary source of vitamin D is the skin, following exposure to ultraviolet radiation. Vitamin D is well known for its effects on stimulating calcium absorption and is thus essential for maintenance of normal bone. It is also important for muscle function and has more recently been implicated in protection against several diseases including diabetes.
Katie M, Dixon, Rebecca S, Mason
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The primary source of vitamin D is the skin, following exposure to ultraviolet radiation. Vitamin D is well known for its effects on stimulating calcium absorption and is thus essential for maintenance of normal bone. It is also important for muscle function and has more recently been implicated in protection against several diseases including diabetes.
Katie M, Dixon, Rebecca S, Mason
openaire +2 more sources
Clinical Endocrinology, 1974
SUMMARYDuring the past decade, an explosion of information has become avdable on the metabolism and function of vitamin D whch is of great importance to clinicians in the treatment of metabolic bone disease. We have learned that vitamin D is the precursor of at least one hormone and that ths hormone carries out functions in calcium and phosphorus ...
M F, Holick, H F, DeLuca
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SUMMARYDuring the past decade, an explosion of information has become avdable on the metabolism and function of vitamin D whch is of great importance to clinicians in the treatment of metabolic bone disease. We have learned that vitamin D is the precursor of at least one hormone and that ths hormone carries out functions in calcium and phosphorus ...
M F, Holick, H F, DeLuca
openaire +4 more sources
New England Journal of Medicine, 1969
A history of vitamin D has been provided, dating from the earliest description of rickets, the disease resulting from vitamin D deficiency, to a current understanding of vitamin D metabolism and the mechanism of action of its hormonal form in regulating gene expression in target organs.
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A history of vitamin D has been provided, dating from the earliest description of rickets, the disease resulting from vitamin D deficiency, to a current understanding of vitamin D metabolism and the mechanism of action of its hormonal form in regulating gene expression in target organs.
openaire +5 more sources
Vitamin D and Sleep Regulation: Is there a Role for Vitamin D?
Current Pharmaceutical Design, 2020Background: Vitamin D exerts multiple pleiotropic effects beyond its role in calcium-phosphate metabolism. Growing evidence suggests an association between hypovitaminosis D and sleep disorders, thus increasing the interest in the role of this vitamin in the regulatory mechanisms of the sleep-wake cycle.
Fiammetta Romano +7 more
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