Results 111 to 120 of about 15,055,784 (304)

The role of vitamin d deficiency towards cognitive deficit of schizophrenia [PDF]

, 2020
Background: Vitamin D receptor (VDR) discovery in the brain tissue demonstrates clearly that vitamin D has a significant role in the development of the brain.
Aryati, Kristanti Sulistyo Rahayu, Azimatul Karimah   +2 more
core   +1 more source

The importance of bone health for pediatric athletes: From juvenile osteochondritis dissecans to relative energy deficiency in sports

Journal of the Pediatric Orthopaedic Society of North America
: Vitamin D is pivotal for bone health, muscle strength, recovery, and overall athletic performance. This article discusses the effects of vitamin D deficiency among athletes, with a specific focus on its connection to sports-related conditions like ...
Louise Atadja, MD, Jennifer Beck, MD, Corinna Franklin, MD   +2 more
doaj   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Correlational study of vitamin D deficiency and dyslipidemia among adult Libyan population

Vitamin D deficiency is a public health concern affecting many individuals as it is highly prevalent in all parts of the world. Recent studies have reported an association of vitamin D deficiency with cardiometabolic alterations such as dyslipidemia. The
Apoajela A. Ahmed
core   +1 more source

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

Advanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu, Jingzhe Wang, Xu Chen, Yuntong Yang, Ping Wei, Han Xie, Honghao Wang, Chunyu Zhang, Siyi Xu, Qi Wang, Chunlong Zhong, Jing Zhang   +11 more
wiley   +1 more source

Is Vitamin D Deficiency Prevalent in Healthy 6-year-old Children in Isfahan City?

مجله دانشکده پزشکی اصفهان, 2007
BACKGROUND: Vitamin D is essential for the maintenance of good health, and vitamin D deficiency has been reported from many countries including sunny ones.
Mehdi Salek, Homayoun Rafati, Mahin Hashemipour, Pouneh Memar Ardestani, Hossein Nezhadnik, Masoud Amini, Seyed Mohsen Hosseini   +6 more
doaj  

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

The Effect of Vitamin D Deficiency on the Severity of Bronchiolitis in Infants

, 2017
Aim: This study was conducted to investigate the effect of vitamin D deficiency on the severity of bronchiolitis in infants who were hospitalized for treatment. Materials and Methods: The infants who were followed up in our hospital and monitored due to
Meltem Erol, Emrah Can, Özlem Bostan Gayret, Özgül Yiğit, Hüseyin Kaya, Şahin Hamilçıkan   +5 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

The effects of vitamin D supplementation on the incidence of pneumonia in infants and young children in Kabul, Afghanistan: a double blind randomized controlled trial [PDF]

Afghanistan has one of the highest infant mortalities in the world, and pneumonia is one of the main killers. Moreover, Dietary intake of vitamin D is low and exposure to sunlight is limited due to widespread use of Burqa by women.
Maroof, Zabihullah
core   +1 more source