Results 191 to 200 of about 308,942 (253)

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Impact of Vitamin D Deficiency and VDR<i>TaqI</i> Polymorphism on Diabetic Retinopathy Risk Among T2DM Ethiopian Population. [PDF]

Food Sci Nutr
Melake A, Alamnie G, Mekonnen M.
europepmc   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

RETRACTION: Association Between Vitamin D Deficiency and Diabetic Foot Ulcer Wound in Diabetic Subjects: A Meta-Analysis. [PDF]

Int Wound J
europepmc   +1 more source

A new perspective on bone development in vitamin D deficiency-associated obese children. [PDF]

Sci Rep
Wang T, Wang H, Zhang ZY, Chang TZ, Yu YT, Miao DS, Zhang BJ, Qiu WX, Zhang CY, Tong X.   +9 more
europepmc   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

Cancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, Hong Zhu, Zeyang Ding, Wanguang Zhang   +12 more
wiley   +1 more source

Prevalence of Vitamin D Deficiency Among Healthy Young Adults at Kuwait University. [PDF]

Cureus
Jamali MA, Abdeen SM, Mathew TC.
europepmc   +1 more source

Anchored in Sole Ingredient Concentration: Numerical Values and Consumer Perceptions of Healthfulness and Quality

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Numerical values often serve as anchors in consumer evaluations, potentially shaping perceptions even in the absence of objective reference points. This research introduces the Concentrated Effect, which posits that numerical values indicating the amount of a sole ingredient in a food product can enhance perceptions of ingredient concentration.
Shahin Sharifi
wiley   +1 more source

Are Pediatric Cancer Patients a Risk Group for Vitamin D Deficiency? A Systematic Review. [PDF]

Cancers (Basel)
Alexandru A, Ivan CS, Tanasescu S, Oprisoni LA, Dragomir TL, Varga NI, Mateescu D, Diaconu M, Margan MM, Boeriu E.   +9 more
europepmc   +1 more source