Results 191 to 200 of about 15,055,784 (304)

Maternal Factors Modifying the Link Between Genetic Risk for Autism and Developmental Milestones

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Although common genetic liability—quantified through polygenic risk scores (PRS)—accounts for substantial variance in autism spectrum disorder (ASD) liability, how prenatal environmental exposures interact with genetic predisposition to shape developmental outcomes remains poorly understood. Using the data from Autism Genetic Resource Exchange
Liliana D'Alesio   +4 more
wiley   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

open access: yesAngewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda   +8 more
wiley   +2 more sources

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen   +5 more
wiley   +1 more source

Vitamin D Deficiency Participates in Depression of Patients with Diabetic Peripheral Neuropathy by Regulating the Expression of Pro-Inflammatory Cytokines

open access: yes
Jingjing Zhou,1,2 Dongfeng Li,2 Youmin Wang1 1Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230001, People’s Republic of China; 2Department of Endocrinology, The Second People’s Hospital of Lu’an ...
Li D, Wang Y, Zhou J
core  

Updated perspectives on vitamin D deficiency, screening, supplementation and clinical guidance. [PDF]

open access: yesCardiovasc Diabetol Endocrinol Rep
Dina MA   +6 more
europepmc   +1 more source

Association between vitamin D deficiency and type 2 diabetes in an Indigenous Brazilian population. [PDF]

open access: yesArch Endocrinol Metab
Santos HCD   +5 more
europepmc   +1 more source

Gold Single‐Atom Catalysts Enable Selective Shuttle Hydrochlorination of Alkynes

open access: yesAngewandte Chemie International Edition, EarlyView.
Gold single‐atom catalysts on activated carbon enable heterogeneous shuttle hydrochlorination of terminal alkynes to vinyl chlorides with high chemo‐ and stereo‐selectivity thanks to cooperation between Au(I) sites and the support. The catalytic system combines broad substrate compatibility, simplified separation, and recoverability, paving the way for
Marc‐Eduard Usteri   +8 more
wiley   +1 more source

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