Results 71 to 80 of about 275,782 (257)

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Effect of vitamin D supplementation on blood pressure:a systematic review and meta-analysis incorporating individual patient data [PDF]

, 2015
D-PRESSURE Collaboration: et al.[Importance]: Low levels of vitamin D are associated with elevated blood pressure (BP) and future cardiovascular events.
Alvarez, Jessica, Beveridge, Louise A., Boxer, Rebecca, Dalbeni, Andrea, Gepner, Adam D., Isbel, Nicole M., Jorde, Rolf, Khan, Faisel, Larsen, Thomas, Macdonald, Helen M., Nagpal, Jitender, Petchey, William G., Scragg, Robert, Stricker, Hans, Stroebel, Franziska, Struthers, Allan D., Tangpricha, Vin, Toxqui, Laura, Vaquero, M. Pilar, Wamberg, Louise, Witham, Miles D., Zittermann, Armin   +21 more
core   +4 more sources

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Vitamin D management update: evidence-based guidelines for vitamin D optimization by the Egyptian Academy for bone and muscle health

Egyptian Rheumatology and Rehabilitation
Background Vitamin D plays a crucial role in bone health, calcium homeostasis, and prevention of chronic diseases. Deficiency and insufficiency of vitamin D poses a global health concern, particularly in specific populations such as the elderly ...
Yasser El Miedany, Mathias Toth, Maha Mohamed El Gaafary, Safaa A. Mahran, Waleed Hassan, Mohammed Hassan Abu-Zaid, Walaa Elwakil, Walaa Basyoni Selim, Eman Ahmed Sultan, Ghada Saber Ibraheem, Salwa Galal Moussa   +10 more
doaj   +1 more source

How to do it: Vitamin D supplementation [PDF]

, 2017
Vitamin D testing and supplementation is of great interest to neurologists and their patients. Recommended nutritional intakes of vitamin D in the UK remain focused on bone health, despite increasing evidence for a role outside this area. Here we discuss
Fry, Gavin Giovannoni, Hannah R Cock, Holick, Hollis, Manson, Nielsen, Pakpoor, Peter Brex, Ruth Dobson, Wagner   +10 more
core   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Status of Vitamin D in Childhood-onset Systemic Lupus Erythematosus and its Relation with the Disease Activity

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Objective: This study aims to determine the vitamin D level in childhood-onset systemic lupus erythematosus (cSLE) and its association with disease activity both before and after vitamin D supplementation. Methods: This prospective study was done over 18
Dikpati Mukherjee, Sumantra Sarkar, Suprit Basu, Supratim Datta, Madhumita Nandi, Paramita Das   +5 more
doaj   +1 more source

Prevalence and predictors of vitamin D-deficiency in frail older hospitalized patients

BMC Geriatrics, 2018
Background Vitamin D deficiency is known to be highly prevalent in older persons. However, the prevalence in the subgroup of frail older hospitalized patients is not clear. We sought to investigate the prevalence and predictors of vitamin D deficiency in
Simon Friedrich Boettger, Bjoern Angersbach, Christiane Nicola Klimek, Ana Lemos Monteiro Wanderley, Azim Shaibekov, Lars Sieske, Baigang Wang, Matthias Zuchowski, Rainer Wirth, Maryam Pourhassan   +9 more
doaj   +1 more source

Vitamin D supplementation in pregnancy and early infancy in relation to gut microbiota composition and C. difficile colonization: implications for viral respiratory infections

Gut Microbes, 2020
In Canada and the US, the infant diet is supplemented with vitamin D via supplement drops or formula. Pregnant and nursing mothers often take vitamin D supplements.
Kelsea M. Drall, Catherine J. Field, Andrea M. Haqq, Russell J. de Souza, Hein M. Tun, Nadia P. Morales-Lizcano, Theodore B. Konya, David S. Guttman, Meghan B. Azad, Allan B. Becker, Diana L. Lefebvre, Piush J. Mandhane, Theo J. Moraes, Malcolm R. Sears, Stuart E. Turvey, Padmaja Subbarao, James A. Scott, Anita L Kozyrskyj   +17 more
doaj   +1 more source