Results 91 to 100 of about 31,583,433 (255)

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Wu, Shaoping, Jae-Woong Hwang, Sundar, Isaac K, Sun, Jun, Isaac K. Sundar, Hwang, Jae-woong, Rahman, Irfan, Shaoping Wu, Irfan Rahman, Jun Sun   +9 more
core   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Association of serum vitamin D status with dietary intake in adults with overweight and obesity [PDF]

Pharmacia
Vitamin D deficiency is a widespread problem throughout the world, often resulting from impaired synthesis in the skin and insufficient intake. The present study aimed to provide an in-depth analysis of vitamin D intake in individuals who are normal ...
Maria Nikolova, Kristina Kilova, Lalka Rangelova, Valentina Petkova, Rene Mileva-Popova, Andrey Petrov, Tsvetanka Dzhiganska, Radka Tafradjiiska-Hadjiolova, Vanina Mihaylova, Adolf Alakidi   +9 more
doaj   +3 more sources

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Vitamin E and neurodegeneration

Neurobiology of Disease, 2015
Alpha-tocopherol (vitamin E) is a plant-derived antioxidant that is essential for human health. Studies with humans and with animal models of vitamin E deficiency established the critical roles of the vitamin in protecting the central nervous system, and
Lynn M. Ulatowski, Danny Manor
doaj   +1 more source

Vitamin D Status of HIV-Infected Women and its Association with HIV Disease Progression, Anemia, and Mortality. [PDF]

, 2010
Vitamin D has a potential role in slowing HIV disease progression and preventing mortality based on its extensive involvement in the immune system; however, this relationship has not been examined in large studies or in resource-limited settings. Vitamin
Mugusi, Ferdinand M, Mugusi, F.M, Hunter, D., Spiegelman Donna, Mehta, Saurabh, Hertzmark, E., Saurabh Mehta, Mugusi, Ferdinand M., Spiegelman, D., Fawzi, W.W, Hertzmark Ellen, Mugusi Ferdinand M., Edward Giovannucci, Wafaie W Fawzi, Fawzi, Wafaie, Spiegelman, Donna, Fawzi Wafaie W., Msamanga, G.I, Said Aboud, Giovannucci Edward, Hunter David, Aboud, Said, Hertzmark, Ellen, Giovannucci, E., Msamanga Gernard I., Ellen Hertzmark, Ferdinand M Mugusi, David Hunter, Mehta Saurabh, Aboud Said, Aboud, S., Msamanga, Gernard I., Hunter, David, Giovannucci, Edward, Msamanga, Gernard I, Donna Spiegelman, Gernard I Msamanga, Fawzi, Wafaie W   +37 more
core   +2 more sources

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source