Results 111 to 120 of about 31,583,433 (255)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Fat-soluble vitamin deficiency in children with neurodevelopmental disorders: a cross-sectional study

BMC Medicine
Background Neurodevelopmental disorders (NDDs) affect 15–20% of children worldwide, and emerging evidence suggests nutritional status may influence neurodevelopmental outcomes.
Jingjing Rao, Xiaomei Wang, Ping Zhou, Yun Xiang, Lei Xi, Changzhen Li   +5 more
doaj   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Assessment of Micronutrient Deficiencies in Exclusively Breastfed Infants: A Cross-Sectional Study

Children
Background/Objectives: Micronutrient deficiencies during infancy remain a major public health concern, particularly in developing countries. Although exclusive breastfeeding is the optimal source of nutrition for infants up to six months of age, limited ...
Burçe Emine Dörtkardeşler, Merve Tosyali, Feyza Koç, Oya Baltalı Hıdır, Güneş Ak   +4 more
doaj   +1 more source

Ataxia due to vitamin E deficiency: A case report and updated review. [PDF]

Clin Case Rep, 2022
Thapa S, Shah S, Chand S, Sah SK, Gyawali P, Paudel S, Khanal P.   +6 more
europepmc   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Effect of Cholesterol, Iron and Vitamin E on Protamine Deficiency and DNA Fragmentation of Male Rabbit Sperm

مجله دانشکده پزشکی اصفهان, 2014
Background: The role of vitamin E as an antioxidant and iron-containing compounds on DNA is not well defined. So, recent study was carried out to determine the role of vitamin E and iron, as both separate and combined effect on sperm protamine deficiency
Nazem Ghasemi, Gholam-Reza Dashti, Fatimah Amoozgar, Seyed-Ahmad Vaez   +3 more
doaj  

Serum Metabolic Characterization of Vitamin E Deficiency in Holstein Cows during the Transition Period Based on Proton Nuclear Magnetic Resonance Spectroscopy. [PDF]

Animals (Basel), 2023
Song Y, Wang H, Sun R, Chang J, Tang J, Bai Y, Xia C.   +6 more
europepmc   +1 more source

Nutrition of Indonesian women during pregnancy and lactation: a focus on vitamin A and iron [PDF]

, 2001
Nutrition during pregnancy is important for women's health, outcome of pregnancy and child survival. A community-based study was conducted in a rural area of West Java, Indonesia to investigate 1) the effect of weekly vitamin A and iron supplementation ...
Muslimatun, S.
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