Results 41 to 50 of about 146,304 (253)

Association between serum vitamin A and E status and recurrent respiratory tract infections in children: a propensity score-matched study

BMC Pediatrics
Background Recurrent respiratory tract infections (RRTIs) and vitamin deficiencies are significant public health concerns in pediatrics. While the immunomodulatory effects of vitamins A and E are widely recognized, their specific roles and associations ...
Yuan Feng, Jing Peng, Xiaolin Cui, Huan Li, Si Luo, Yinfei Zhou, Hongping Li   +6 more
doaj   +1 more source

Clinical study of experimentally induced vitamin E and selenium deficiency in Awassi ewes and their newborn lambs

The Iraqi Journal of Veterinary Medicine, 2012
Experimental induction of vitamin E and selenium deficiency by deficient diet was carried out on Awassi ewes and their newborn lambs. The clinical signs were characterized by sudden death in 4 lambs out of 14 lambs in deficient group and other lambs ...
H. K. Abood
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Vitamin A nutritional status in high- and low-income postpartum women and its effect on colostrum and the requirements of the term newborn

Jornal de Pediatria, 2018
Objective: To evaluate the vitamin A status in serum and colostrum of postpartum women with different socioeconomic status, comparing the colostrum retinol supply with the vitamin A requirement of the newborn.
Cristiane Santos Sânzio Gurgel, Evellyn C. Grilo, Larissa Q. Lira, Débora G.F. Assunção, Priscila G. Oliveira, Larisse R.M. de Melo, Silvia V. de Medeiros, Luanna C. Pessanha, Roberto Dimenstein, Clélia O. Lyra   +9 more
doaj   +1 more source

Vitamin E Deficiency in Developing Countries [PDF]

Food and Nutrition Bulletin, 2011
In addition to its role as a potent antioxidant, vitamin E is involved in a wide range of physiological processes, ranging from immune function and control of inflammation to regulation of gene expression and cognitive performance. Results from multiple studies suggest that poor nutritional status and higher prevalence of other oxidative stressors such
Daphna K, Dror, Lindsay H, Allen
openaire   +2 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Sensory Ataxia and Vitamin E Deficiency

Pediatric Neurology Briefs, 1994
A progressive limb and gait ataxia, distal loss of proprioception and vibration sense, and areflexia, caused by a prolonged and severe vitamin E deficiency, are reported in four patients evaluated as adults at King’s College, Hammersmith Hospital, and ...
J Gordon Millichap
doaj   +1 more source