Results 41 to 50 of about 307,837 (302)

Serum 25-hydroxyvitamin D levels in hospitalized adults with community-acquired pneumonia [PDF]

, 2018
Introduction: Community‐acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Several studies have shown an association between vitamin D deficiency and increases susceptibility to respiratory tract infections ...
Bool, British Thoracic Society Research Committee and the Public Health Laboratory Service, Charlson, Cukic, Fine, Gombart, Haan, Huang, Jolliffe, Kamen, Karonova, Kim, Kochanek, Lim, Liu, Lu, Luna, Mandell, Niederman, Pletz, Remmelts, Ross, Røysted, Schnoor, Schöttker, Toubi, Welte, Youssef   +27 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Elimination of avoidable blindness due to cataract: where do we prioritize and how should we monitor this decade? [PDF]

, 2012
BACKGROUND: In the final push toward the elimination of avoidable blindness, cataract occupies a position of eminence for the success of the Right to Sight initiative. AIMS: Review existing situation and assess what monitoring indicators may be useful to
John, Neena, Murthy, Gudlavalleti VS, Pant, Hira B, Shamanna, Bindiganavale R   +3 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ataxia with Vitamin E Deficiency

Pediatric Neurology Briefs, 1997
Vitamin E adminstration (100 U/kg daily) resulted in improvements in ataxia, motor strength, and mobility in 2 siblings of a consanguineous Bedouin family with Friedreich ataxia and low serum vitamin E levels treated at Soroka Medical Center, Beer Sheva,
J Gordon Millichap
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Prevalência da carência de ferro e sua associação com a deficiência de vitamina A em pré-escolares Prevalence of iron deficiency and its association with vitamin A deficiency in preschool children

Jornal de Pediatria, 2005
OBJETIVO: Estimar a carência de ferro na população estudada e verificar se isso se associa à falta de vitamina A. MÉTODOS: Foram estudadas 179 crianças com idade > 24 meses e < 72 meses, sem diarréia e/ou febre no momento da coleta.
Ivan S. Ferraz, Júlio C. Daneluzzi, Hélio Vannucchi, Alceu A. Jordão Jr., Rubens G. Ricco, Luiz A. Del Ciampo, Carlos E. Martinelli Jr., Alexander A. D’Angio Engelberg, Luis R. C. M. Bonilha, Viviane I. C. Custódio   +9 more
doaj   +1 more source

Interactions and potential implications of Plasmodium falciparum-hookworm coinfection in different age groups in south-central Côte d'Ivoire [PDF]

, 2012
BACKGROUND: Given the widespread distribution of Plasmodium and helminth infections, and similarities of ecological requirements for disease transmission, coinfection is a common phenomenon in sub-Saharan Africa and elsewhere in the tropics. Interactions
A Spiegel, AA Righetti, AH Shankar, Ahou-Yah G. Koua, Aurélie A. Righetti, C Menendez, CJL Murray, D Filmer, DA Ross, DI Thurnham, DL Doolan, Dominik Glinz, EK N'Goran, EK N'Goran, Eliézer K. N'Goran, FC Hartgers, FK Grant, FP Mockenhaupt, Francis Mutuku, G Jones, G Weiss, GC Melo, HR Choudhury, J Langhorne, J Murray, JD Cook, JG Erhardt, JK Kung'u, JL Gorstein, Jürg Utzinger, KE Lyke, KP West Jr, L Brutus, L Serghides, Lukas G. Adiossan, M Nacher, M Zuk, MD Taylor, N Katz, NJ Yatich, NR de Silva, P Galan, PJ Hotez, Richard F. Hurrell, Rita Wegmüller, RJ Stoltzfus, RL Pullan, RM Maizels, RW Snow, S Brooker, S Brooker, SL Becker, Sébastien Niamké, Y Dror   +53 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Evidence for the Necessity to Systematically Assess Micronutrient Status Prior to Bariatric Surgery [PDF]

, 2018
Background: Bariatric surgery has been proven the most effective treatment of morbid obesity, but micronutrient deficiency following bariatric surgery is a major concern.
Ernst, Barbara, Schmid, Sebastian, Schultes, Bernd, Thurnheer, Martin   +3 more
core