Results 31 to 40 of about 153,961 (306)

Vitamin D supplementation as an adjuvant therapy for patients with T2DM : an 18-month prospective interventional study [PDF]

, 2012
Background Vitamin D deficiency has been associated with impaired human insulin action, suggesting a role in the pathogenesis of diabetes mellitus type 2 (T2DM).
Al-Othman, Abdulaziz, Osama Moharram, Alokail Majed S, El-Kholie, Emad, Kumar Sudhesh, Sabico, Shaun, Sudhesh Kumar, Sabico Shaun, George P Chrousos, Al-Othman Abdulaziz, Alokail, Majed S., Al-Daghri, Nasser M., Al-Saleh, Yousef, Majed S Alokail, Al-Saleh Yousef, Yousef Al-Saleh, Alkharfy Khalid M, Chrousos, George P., Kumar, Sudhesh, Chrousos George P, Abdulaziz Al-Othman, Emad El-Kholie, Moharram Osama, Nasser M Al-Daghri, Shaun Sabico, El-Kholie Emad, Moharram, Osama, Al-Daghri Nasser M, Alkharfy, Khalid M., Khalid M Alkharfy   +29 more
core   +1 more source

The effect of vitamin D deficiency on the RANKL/OPG ratio in rats

Journal of Oral Biology and Craniofacial Research, 2022
The aim of this study was to determine the effect of vitamin D deficiency on the RANKL/OPG ((Receptor Activator of Nuclear Factor Kappa B Ligand/Osteoprotegerin) ratio in the serum blood levels.
Rawan M. Khalaf, Abdullazez A. Almudhi
doaj   +1 more source

Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin d in mice fed a high-fat diet [PDF]

, 2014
The role of vitamin D in curtailing the development of obesity and comorbidities such as the metabolic syndrome (MetS) and type 2 diabetes has received much attention recently. However, clinical trials have failed to conclusively demonstrate the benefits
Feelisch, Martin, Weller, Richard B; id_orcid, Matthews, Vance, Jacoby, Peter, Endersby, Raelene, Hart, Prue H, Geldenhuys, Sian, Weller, Richard B., Hart, Prue H., Gorman, Shelley   +9 more
core   +1 more source

Beyond deficiency prevention: meteorological determinants and nonlinear associations of maternal vitamins D, A, and E with perinatal outcomes in 10,824 Chinese pregnancies

Frontiers in Nutrition
ObjectiveTo examine meteorological factors associated with maternal vitamins D, A, and E and their associations with delivery and neonatal outcomes in central China.MethodsIn this retrospective cross-sectional analysis of 10,824 third-trimester women who
Changzhen Li, Shiyong Deng, Ping Zhou, Jingjing Rao, Yun Xiang, Lei Xi, Xiaomei Wang   +6 more
doaj   +1 more source

Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K-1) in severe acute liver disease

, 2005
Background/Aims: In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K-1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy ...
Pereira, SP, David Rowbotham, Stephen P. Pereira, Sarah Fitt, Fitt, S, Pereira, S P, Wendon, J, Roger Williams, Williams, R, Julia Wendon, Rowbotham, D, Martin J. Shearer, Shearer, MJ, Shearer, M J   +13 more
core   +1 more source

Vitamin E-induced coagulopathy in a young patient: a case report

Journal of Medical Case Reports, 2023
Background High-dose vitamin E intake is known to inhibit vitamin K-derived coagulation factor synthesis, which can cause serious bleeding events such as gastrointestinal bleeding and intracranial hemorrhage.
Ritika Abrol, Reshma Kaushik, Deepak Goel, Sonu Sama, Rajeev Mohan Kaushik, Mansi Kala   +5 more
doaj   +1 more source

Deficiency of vitamins C and E in women of childbearing age in Brazil: a systematic review and meta-analysis

São Paulo Medical Journal, 2021
BACKGROUND: Despite the several options available for supplements containing vitamins C and E, evidence regarding the prevalence of deficiency or insufficiency of these vitamins is weak.
Rosa Camila Lucchetta, Sophia de Andrade Cavicchioli, Ana Luísa Rodriguez Gini, Marcela Forgerini, Fabiana Rossi Varallo, Mariane Nunes de Nadai, Fernando Fernandez-Llimos, Patricia de Carvalho Mastroianni   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Hospital admissions for vitamin D related conditions and subsequent immune-mediated disease: record-linkage studies.

, 2013
BACKGROUND: Previous studies have suggested that there may be an association between vitamin D deficiency and the risk of developing immune-mediated diseases.
Giulio Disanto, Michael J Goldacre, Goldacre, R, Sreeram V Ramagopalan, Gavin Giovannoni, Raph Goldacre, Ramagopalan, SV, Goldacre, MJ, Goldacre, Michael, Giovannoni, G, Disanto, G   +10 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source