Results 291 to 300 of about 206,382 (334)
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Hämostaseologie, 2012
SummaryFor the last decades, anticoagulation for stroke prevention in atrial fibrillation (AF) as well as for the prophylaxis and long-term treatment of venous thromboembolism has been entirely based on vitamin K antagonists (VKA). Although very effective under optimal conditions, long-term treatment with these drugs is flawed by the fact that the time
Andrew Davenport +34 more
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SummaryFor the last decades, anticoagulation for stroke prevention in atrial fibrillation (AF) as well as for the prophylaxis and long-term treatment of venous thromboembolism has been entirely based on vitamin K antagonists (VKA). Although very effective under optimal conditions, long-term treatment with these drugs is flawed by the fact that the time
Andrew Davenport +34 more
openaire +3 more sources
2023
Abstract Since the 1950s, vitamin K antagonists have been used for the prevention and treatment of venous and arterial thrombotic disorders. They have a narrow therapeutic window. To ensure efficacy and safety, close monitoring of the anticoagulation status is mandatory. Dietary and drug interactions are common.
Freek W.A. Verheugt, Marc A. Brouwer
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Abstract Since the 1950s, vitamin K antagonists have been used for the prevention and treatment of venous and arterial thrombotic disorders. They have a narrow therapeutic window. To ensure efficacy and safety, close monitoring of the anticoagulation status is mandatory. Dietary and drug interactions are common.
Freek W.A. Verheugt, Marc A. Brouwer
openaire +1 more source
2018
This new, third edition of The ESC Textbook of Cardiovascular Medicine is a ground-breaking initiative from the European Society of Cardiology that transforms reference publishing in cardiovascular medicine to better serve the changing needs of the global cardiology community.
Jespersen, Jørgen, Skov, Jane
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This new, third edition of The ESC Textbook of Cardiovascular Medicine is a ground-breaking initiative from the European Society of Cardiology that transforms reference publishing in cardiovascular medicine to better serve the changing needs of the global cardiology community.
Jespersen, Jørgen, Skov, Jane
openaire +3 more sources
Vitamin K antagonist-associated microscopic hematuria
The American Journal of the Medical Sciences, 2022Vitamin K antagonists (VKA) are the most widely used anticoagulants for the prevention of thrombotic events. Several renal adverse effects have been associated with the use of VKA. The main aim of our study was to explore the association between international normalized ratio (INR) levels and microscopic hematuria in patients with VKA.We performed a ...
Amir, Shabaka +6 more
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Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome
Annals of Internal Medicine, 2019Antiphospholipid antibody syndrome (APS) is an acquired thrombophilic disorder in which vascular thrombosis (venous or arterial) and pregnancy losses may occur in the presence of persistent antiphospholipid antibodies (aPLs) (14).
J. Ordi‐Ros +10 more
semanticscholar +1 more source
Vitamin K Antagonists: Beyond Bleeding
Seminars in Dialysis, 2014AbstractWarfarin is the most widely used oral anticoagulant in clinical use today. Indications range from prosthetic valve replacement to recurrent thromboembolic events due to antiphospholipid syndrome. In hemodialysis (HD) patients, warfarin use is even more frequent than in the nonrenal population due to increased cardiovascular comorbidities.
Thilo, Krüger, Jürgen, Floege
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Vitamin K antagonists and emergencies
European Journal of Emergency Medicine, 2018The recent emergence of ‘non-VKA’ oral anticoagulants may have led to some forgetting that vitamin K antagonists (VKA) are by far the most widely prescribed oral anticoagulants worldwide. Consequently, we decided to summarize the information available on them. This paper presents the problems facing emergency physicians confronted with patients on VKAs
Lapostolle, Frédéric +6 more
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Pros and Cons of Vitamin K Antagonists and Non–Vitamin K Antagonist Oral Anticoagulants
Seminars in Thrombosis and Hemostasis, 2015Anticoagulant treatment can be currently instituted with two different classes of drugs: the vitamin K antagonists (VKAs) and the newer, "novel" or non-vitamin K antagonist oral anticoagulant drugs (NOACs). The NOACs have several practical advantages over VKAs, such as the rapid onset/offset of action, the lower potential for food and drug interactions,
RIVA, NICOLETTA, AGENO, WALTER
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