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The Southeast Asian journal of tropical medicine and public health, 1995
Vitamin K (phylloquinone, K1; menaquinone, K2) functions as an essential cofactor for the synthesis of the coagulation protein factors II, VII, IX, X and protein C and S by promoting a unique post-translational modification of specific glutamic acid residues to gamma-carboxylglutamic acid, thus mediating calcium binding to phospholipid surfaces ...
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Vitamin K (phylloquinone, K1; menaquinone, K2) functions as an essential cofactor for the synthesis of the coagulation protein factors II, VII, IX, X and protein C and S by promoting a unique post-translational modification of specific glutamic acid residues to gamma-carboxylglutamic acid, thus mediating calcium binding to phospholipid surfaces ...
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Vitamin K Deficiency and Breast-feeding
Archives of Pediatrics & Adolescent Medicine, 1983Hemorrhagic disease of the newborn was described in 1894 by Townsend.1It occurs in the first week of life, independent of trauma, anoxia, or infection, and appears to be a self-limiting condition if unassociated with life-threatening hemorrhage. It is caused by vitamin K deficiency, which has been reported in several infants 4 to 8 weeks old.
M E, O'Connor +3 more
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Vitamin K–Dependent Coagulation Factors Deficiency
Seminars in Thrombosis and Hemostasis, 2009All vitamin K-dependent coagulation factors require normal function of gamma-glutamyl carboxylase and vitamin K epoxide reductase enzyme complex (VKORC1). Heritable dysfunction of gamma-glutamyl carboxylase or of the VKORC1 complex results in the secretion of poorly carboxylated vitamin K-dependent proteins that play a role in coagulation.
Benjamin, Brenner +3 more
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Vitamin K Deficiency in Breastfed Infants
The Journal of Pediatrics, 1985Vitamin K is required for gamma carboxylation of a number of proteins, most of which are involved in haemostasis. Bleeding is the main clinical problem observed in vitamin K deficiency.
R, von Kries +3 more
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Vitamin K deficiency — Late onset intracranial haemorrhage
European Journal of Paediatric Neurology, 1998A retrospective study is presented of the clinical features and outcome of late onset haemorrhagic disease due to vitamin K deficiency in 11 babies who were admitted to the emergency or child neurology unit during a 4-year period (January 1994-December 1997). The disease occurred in infants between 30 and 119 days of age (mean: 56+/-24 days).
Çalişkan, Mine +5 more
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Oral anticoagulation and vitamin K deficiency
Hämostaseologie, 2014SummaryA 61-year old woman with atrial fibrillation developed macrohaematuria during anticoagulant treatment with a direct oral factor Xa inhibitor for stroke prevention. Abnormal results of coagulation assays were first interpreted as an effect of the anticoagulant. However, upon further testing diagnosis of vitamin K deficiency was established. After
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Vitamin K Deficiency Bleeding: An Ounce of Prevention
Neonatal Network, 2020C. McPherson
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VITAMIN-K DEFICIENCY IN THE NEWBORN
The Lancet, 1977van Doorm, J.M., Hemker, H.C.
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