Results 41 to 50 of about 40,694 (303)

The relationships between vitamin K and cognition: a review of current evidence [PDF]

open access: yes, 2019
Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico   +7 more
core   +2 more sources

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]

open access: yes, 2008
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR   +7 more
core   +2 more sources

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Temporal association between serious bleeding and immunization: vitamin K deficiency as main causative factor

open access: yesBMC Pediatrics, 2020
Background Bleeding as an adverse event following immunization (AEFI) that is rarely reported in children, although it can be a parental concern. Bleeding episodes ranging in severity from mild to severe and defined as any external and/or internal ...
Susi Susanah   +9 more
doaj   +1 more source

The Impact of Vitamin K2 (Menaquionones) in Children’s Health and Diseases: A Review of the Literature

open access: yesChildren, 2022
Vitamin K2 activates vitamin K-dependent proteins that support many biological functions, such as bone mineralization, the inhibition of vascular stiffness, the improvement of endothelial function, the maintenance of strong teeth, brain development ...
Agnieszka Kozioł-Kozakowska   +1 more
doaj   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

open access: yesHepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat   +22 more
wiley   +1 more source

Unusual Manifestation of Vitamin K Deficiency, Nodular Purpura: A Case Series

open access: yesIndian Dermatology Online Journal
Vitamin K deficiency is a common entity in infancy characterized by bleeding from various sites, intracranial bleeding being the most commonly reported feature.
Sumedha Ballal   +4 more
doaj   +1 more source

Effect of Ferric Sodium EDTA administration, in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine, on cardiovascular risk evaluation: exploration of the HRV frequency domain [PDF]

open access: yes, 2019
diseases. Using the Heart Rate Variability (HRV) analysis is possible to provide an evaluation of the safety and the effectiveness of intervention.
Curcio, A.   +6 more
core   +1 more source

Neglected vitamin K deficiency causing coagulation dysfunction in an older patient with pneumonia: a case report

open access: yesBMC Geriatrics, 2022
Background The development of coagulation disorders can be dangerous and fatal in the older people, especially those with multiple medical conditions. Vitamin K-dependent coagulation disorders are easily overlooked when anticoagulant drugs are not used ...
Qiaoping Wu, Lufeng Wang, Rongqing Zhao
doaj   +1 more source

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