Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]
, 2019 Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S +22 more
core +3 more sources
Increased Risk of Metabolic Syndrome in Patients with Vitiligo
Balkan Medical Journal, 2017 The risk of developing metabolic syndrome is increased in patients with vitiligo. The poor clinical features of vitiligo, such as active, extended and segmental vitiligo with an increased duration of time, are independent predictors for developing ...
Hatice Ataş, Müzeyyen Gönül
doaj +1 more source
MicroRNAs: Emerging players in the pathogenesis of vitiligo
Frontiers in Cell and Developmental Biology, 2022 Vitiligo is an autoimmune skin disease characterized by presence of pale patchy areas of depigmentation. MicroRNAs (miRNAs) are important regulators of gene expression and play significant roles in diverse biological and pathological processes ...
Xin Yu +5 more
doaj +1 more source
A proposed scoring system for assessing the severity of actinic keratosis on the head: actinic keratosis area and severity index [PDF]
, 2017 Background: Actinic keratosis (AK) severity is currently evaluated by subjective assessment of patients. Objectives: To develop and perform an initial pilot validation of a new easy-to-use quantitative tool for assessing AK severity on the head ...
Arkachaisri +27 more
core +1 more source
A clinico-epidemiological study on childhood vitiligo
Indian Journal of Paediatric Dermatology, 2016 Introduction: Vitiligo is a disorder of melanocytes which may have a significant effect on the psyche of a patient. Aims: To study the clinical profile of the patients with childhood vitiligo and see the association of vitiligo with other autoimmune ...
Neerja Puri
doaj +1 more source
Study of metabolic syndrome in patients of Vitiligo: A single-center observational study
Asian Journal of Medical Sciences, 2022 Background: Metabolic syndrome (MetS) has been observed in patients with vitiligo. Literature suggests that there is some link between vitiligo and MetS. Autoimmunity, oxidative stress, and decreased number of melanocytes are involved in its pathogenesis.
Vishal Gourh +3 more
doaj +1 more source
Clinical Features of Vitiligo and Social Impact on Quality of Life
Dermatology Practical & Conceptual, 2023 Vitiligo is the most common cause of depigmentation and its estimated worldwide prevalence ranges from 0.5% to 2%. The disease is characterized by the development of white macules resulting from a loss of epidermal melanocytes.
Seneschal Julien
doaj +1 more source
Variant of TYR and Autoimmunity Susceptibility Loci in Generalized Vitiligo. [PDF]
, 2010 BACKGROUND Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other autoimmune diseases. METHODS To identify generalized
Alain Taïeb +29 more
core +3 more sources
PHP58 A Mediação De Conflitos Na Ação Fiscalizatoria Do Setor De Saúde Suplementar Brasileiro [PDF]
, 2009 Background Punch grafting is a simple and frequently used technique for the treatment of stable vitiligo, resistant to medical therapy. However, studies reporting long-term results are exceptional.
Fongers, A. +5 more
core +14 more sources
Lip vitiligo: a clinico-epidemiological study in a tertiary hospital of South India
Pigment International, 2023 Vitiligo is a common autoimmune pigmentary disorder characterized by destruction of functional melanocytes resulting in the appearance of depigmented patches on the skin and mucosa. These lesions pose a cosmetic challenge.
A. S Savitha +3 more
doaj +1 more source