Results 41 to 50 of about 29,446 (242)
Clinical characteristics of late-onset vitiligo in an Iranian population
Dermatologica Sinica, 2012 Background: The age of onset of vitiligo is before 20 years in approximately in 50% of patients, and its incidence decreases with increasing age. In this study, our aim was to analyze the epidemiological and clinical factors of patients with late-onset ...
Iraj Esfandiarpour, Saeedeh Farajzadeh
doaj +1 more source
Advanced Science, EarlyView.Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan +13 more
wiley +1 more source
An investigation into the role of autoimmunity in vitiligo [PDF]
, 2002 Vitiligo is an acquired depigmenting disorder characterised by the loss of functional melanocytes from the cutaneous epidermis. A role for autoimmunity is supported by the presence of circulating antibodies and T lymphocytes which react against ...
Waterman, Elizabeth Ann
core
Case Reports in Dermatological Medicine, 2017 Vitiligo is a disorder of skin pigmentation. It affects approximately 1% of the world’s population. Vitiligo occurs equally between the sexes with no racial predilections.
Chelsea Casey, Stephen E. Weis
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Framing anatomical variation in anatomy textbooks: Language use and its implications
Anatomical Sciences Education, EarlyView.Text mining of anatomy textbooks shows “abnormal” is the most frequently used descriptor for anatomical variation, reinforcing a binary framing. We advocate for explicit teaching of variation as a spectrum, with consistent, neutral terminology and contextualization (prevalence and functional relevance) to support a more nuanced understanding of ...
An‐Di Yim +2 more
wiley +1 more source
An Investigation of Autoantibodies against Tyrosine Hydroxylase in Patients with Vitiligo [PDF]
, 2012 Vitiligo is an acquired idiopathic hypomelanotic skin disorder characterised by depigmented macules due to loss of cutaneous melanocytes. Evidence suggests that autoimmunity plays a role in the pathogenesis of the disease, since antibodies and T cells ...
Rahoma, Sherif
core
Innate immune activation in vitiligo: mechanisms and pathophysiological implications
Frontiers in ImmunologyVitiligo is an autoimmune disease characterized by the progressive destruction of epidermal melanocytes, leading to skin depigmentation. Although significant advances have been made in understanding the pathogenesis of vitiligo, the intricate interplay ...
Yuting Wang +5 more
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Frontiers in Immunology, 2022 Vitiligo is a depigmented skin disorder caused by a variety of factors, including autoimmune, metabolic disturbance or their combined effect, etc.
Zhubiao Ye +10 more
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Clinical Pharmacology &Therapeutics, EarlyView.Ruxolitinib pharmacokinetics (PK) has been characterized in clinical trials but remains poorly documented in real‐world practice. This project aimed to investigate ruxolitinib PK in routine clinical practice, identify factors driving its variability, and explore exposure–response relationships to assess the potential role of therapeutic drug monitoring.
Jérémie Tachet +11 more
wiley +1 more source
Clinico-epidemiological profile of vitiligo patients in Najran Region, Saudi Arabia
Journal of Dermatology and Dermatologic Surgery, 2015 Objectives: To assess the prevalence of vitiligo among patients with dermatological diseases in Najran, South-Western Saudi Arabia, and to explore the epidemiological profile of vitiligo patients in the region. Materials and methods: This single-observer,
Hamad Ayed AL Fahaad
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