Results 51 to 60 of about 46,789 (257)

Innate immune activation in vitiligo: mechanisms and pathophysiological implications

Frontiers in Immunology
Vitiligo is an autoimmune disease characterized by the progressive destruction of epidermal melanocytes, leading to skin depigmentation. Although significant advances have been made in understanding the pathogenesis of vitiligo, the intricate interplay ...
Yuting Wang, Junhua Cao, Xiaomin Liu, Chengcheng Xiong, Da Xu, Fang Bian   +5 more
doaj   +1 more source

Survey and online discussion groups to develop a patient-rated outcome measure on acceptability of treatment response in vitiligo [PDF]

, 2014
BackgroundVitiligo is a chronic depigmenting skin disorder which affects around 0.5-1% of the world’s population. The outcome measures used most commonly in trials to judge treatment success focus on repigmentation.
Batchelor, Jonathan M., Leighton, Paul, Thomas, Kim S., Tour, Selina K., Walker, Dawn-Marie, Yong, Adrian S.W.   +5 more
core   +2 more sources

Symurban Nanocrystals for Advanced Anti-Pollution Skincare [PDF]

, 2020
Several of most common dermatoses worldwide, e.g., psoriasis and atopic dermatitis, are worsened in their clinical picture when the skin is regularly exposed to an increased air pollution level, e.g., particulate matter.
Köpke, Daniel, Pyo, Sung Min
core   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

Development of consensus recommendations on the management of vitiligo and the role of decapeptide in vitiligo by the delphi method

Indian Journal of Dermatology, 2023
Background: Treatment of vitiligo is still a challenge in dermatology. Literature is sparse on the definitive clinical role of basic fibroblast growth factor (bFGF) in vitiligo patients.
Davinder Parsad, Sanjeev Kandhari, Rachita Dhurat, Bela Shah, Imran Majid, Harikishan Kumar Yadalla, Jagdish Sakhiya, Shital Poojary, P Jagadish, Pravin D Banotkar, Ravindra Babu, Y M Shivakumar, S K Bose, Saleem Jamadar, Monal Shah, Bharat Tank, Ravindra Dhabhai, Sanjay Kumar Mittal, Premanshu Bhushan, Akshi Pandita, Vaibhav Barve   +20 more
doaj   +1 more source

Aetiology and treatment of epidermal depigmentory disorder in humans [PDF]

, 2012
The epidermal depigmentary trigger in humans at post-natal level may occur with the toxification of skin organ with the endogenously produced melanocytotoxic hydrogen peroxide and subsequent formation of hydrogen peroxide- melanolipoprotein conjugate ...
S. S. Sawhney
core   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Clinico-epidemiological profile of vitiligo patients in Najran Region, Saudi Arabia

Journal of Dermatology and Dermatologic Surgery, 2015
Objectives: To assess the prevalence of vitiligo among patients with dermatological diseases in Najran, South-Western Saudi Arabia, and to explore the epidemiological profile of vitiligo patients in the region. Materials and methods: This single-observer,
Hamad Ayed AL Fahaad
doaj   +1 more source

Meta-Analysis of Alterations in Regulatory T Cells’ Frequency and Suppressive Capacity in Patients with Vitiligo

Journal of Immunology Research, 2022
Vitiligo is a noncontagious autoimmune skin depigmenting disease. Regulatory T cells (Tregs) play a key role in maintaining peripheral tolerance; however, Tregs’ number, suppressive function, and associated suppressive molecules (FOXP3, IL-10, and TGF-β)
Prashant S. Giri, Jahanvi Mistry, Mitesh Dwivedi   +2 more
doaj   +1 more source

Turner syndrome and associated problems in turkish children: A multicenter study [PDF]

, 2015
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls.
Abacı, A., Abalı, S., Adal, E., Akın, L., Akıncı, A., Akyürek, N., Andıran, N., Anık, A., Atabek, M.E., Ataş, A., Aydın, B.K., Açıkel, C., Baş, F., Baş, S., Baş, V.N., Bereket, A., Binay, Ç., Bolu, S., Bondy, C., Bulan, K., Büyükinan, M., Can, H.D., Cinaz, P., Darcan, Ş., Darendeliler, F., Demir, K., Demirbilek, H., Demirel, F., Doğan, D., Doğan, M., Döneray, H., Dündar, B., Eklioğlu, B.S., Emeksiz, H.C., Ercan, O., Eren, E., Ersoy, B., Evliyaoğlu, O., Fidancı, K., Gökşen, D., Gül, D., Gürbüz, F., Hatun, Ş., Kaba, S., Kara, C., Karagüzel, G., Keskin, M., Kızılay, D., Orbak, Z., Pirgon, Ö., Polat, A., Poyrazoğlu, Ş., Sarı, E., Sağlam, H., Tarım, Ö., Tepe, D., Topaloğlu, A.K., Turan, S., Yeşilkaya, E., Yüksel, B., Çakır, E.D., Çatlı, G., Çelik, N., Çizmecioğlu, F., Ökten, A., Önal, H., Özbek, M.N., Özen, S., Özgen, T., Özhan, Bayram, Özkan, B., Ünüvar, T., Şen, Y., Şimşek, E.   +73 more
core   +1 more source