Results 71 to 80 of about 29,446 (242)

Nail Lichen Planus in Children ‐ Epidemiology, Pathogenesis, Clinical Presentation, and Treatment

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail lichen planus (NLP) is a chronic inflammatory disorder that, while rare in children compared to adults, represents a significant cause of pediatric nail dystrophy that requires early recognition to prevent permanent scarring and nail loss.
Francesca Pampaloni, Matilde Iorizzo
wiley   +1 more source

Triggering of Koebner Phenomenon by Picosecond Laser in a Psoriatic Patient: Clinical and Immunopathologic Insights

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To report the first case of Koebner phenomenon induced by picosecond laser treatment in a patient with psoriasis. We analyzed the clinical and histopathological features and discussed the possible mechanism by which the laser's photomechanical effect triggered the reaction.
Teppei Sakai, Koya Sonoda, Jun Omatsu
wiley   +1 more source

Childhood Vitiligo

American Journal of Clinical Dermatology, 2019
Vitiligo is a common acquired depigmenting skin disease characterized by a progressive loss of functional melanocytes. It may appear from the first years of life to late adulthood. Childhood vitiligo (CV), defined as vitiligo that begins before the age of 12 years, is common and may differ from post-CV in terms of epidemiology, clinical presentation ...
Electra Nicolaidou, Styliani Mastraftsi, Vassiliki Tzanetakou, Dimitrios Rigopoulos   +3 more
openaire   +3 more sources

Risk Factors for Cutaneous Immune‐Related Adverse Events in the Japanese Population: A Retrospective Single‐Center Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe, Kohei Yamakawa, Miyu Kobayashi, Yusuke Saigusa, Yukie Yamaguchi   +4 more
wiley   +1 more source

Exploring and Comparing the Psychosocial Impacts of Vitiligo on a Broader Scale: An International Survey via the Use of Social Media

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Vitiligo is associated with substantial psychosocial burden; however, community‐based patient‐reported data remain limited, and existing instruments may not fully reflect patients' lived experience. This study explored the psychosocial impacts of vitiligo using social media‐based recruitment.
Megan Noda, Mathew Ghodsian, Jonathan Chan   +2 more
wiley   +1 more source

Vitiligo na criança e doença da tireóide Childhood vitiligo and thyroid disease

Anais Brasileiros de Dermatologia, 2009
A associação entre vitiligo e tireoidopatia na criança é discutível. Cinquenta crianças com vitiligo e 40 sem vitiligo foram submetidas às dosagens séricas de anticorpos antitireoide e hormônio tireoestimulante.
Nurimar Conceição Fernandes, Márcia Maria Cajueiro Campos   +1 more
doaj   +1 more source

INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol

BJU International, EarlyView.
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan, Ethan Senior, Jessica Kendall, Jamie B. Oughton, Fiona Collinson, Jon Griffin, Rachel Hubbard, Steven Kennish, Aidan Noon, Derek J. Rosario, Irbaz B. Riaz, Julie Telliez, James W. F. Catto, Syed A. Hussain   +13 more
wiley   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Cutaneous Blood Flow and Adrenoceptor Response Increase in Segmental-Type Vitiligo Lesions [PDF]

, 2009
It has been proposed that two types of vitiligo exist from the physiological and clinical points of view. Nonsegmental- type vitiligo is associated with autoimmune diseases while segmental-type vitiligo results from the dysfunction of sympathetic nerves ...
吳錫山;余幸司;張火龍;吳濱南;余家利, WU, HIS-SHAN;YU, HSIN-SU;CHANG, HUO- LUNG;WU, PIN-NAN;YU, CHIA-LI   +1 more
core  

Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies [PDF]

Vitiligo is a dermatological condition affecting 1% of the global population, characterized by the loss of skin pigmentation. It appears in two main forms: nonsegmental (symmetrical depigmentation) and segmental (localized depigmentation).
Zhussipbek Mukatayev, Almagul Kushugulova, Nurlubek Katkenov, Artur Kovenskiy   +3 more
core   +1 more source