Results 11 to 20 of about 377,437 (162)

Effect of Adjuvant Mitomycin-C on Recurrent Rhegmatogenous Retinal Detachment With Proliferative Vitreoretinopathy Managed by Relaxing Retinotomy and Retinectomy. [PDF]

J Ophthalmol
Purpose: To evaluate the role of adjuvant mitomycin‐C (MMC) use in cases of recurrent rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR) managed by relaxing retinotomy and retinectomy (RR). Methods: A retrospective analysis of consecutive patients undergoing vitreoretinal surgery with RR for RD and PVR was ...
Gürelik İG, Özdemir HB, Köse BG, Acar AB.   +3 more
europepmc   +2 more sources

Leveraging AAV1-Rac1T17N to prevent experimental proliferative vitreoretinopathy [PDF]

Journal of Translational Medicine
Background Platelet-derived growth factor receptor β (PDGFRβ) is the principal PDGFR isoform in retinal pigment epithelial (RPE) cells from the epiretinal membranes of patients with proliferative vitreoretinopathy (PVR).
Duo Li, Minli Linghu, Jisen Tang, Gukun Yang, Chuanwu Li, Hang Yao, Hetian Lei, Yikeng Huang, Xionggao Huang   +8 more
doaj   +2 more sources

Proliferative vitreoretinopathy and its relationship with inflammatory serum biomarkers [PDF]

International Journal of Ophthalmology
AIM: To analyze if a relationship between levels of inflammatory serum biomarkers and severity of primary proliferative vitreoretinopathy (PVR) exists. METHODS: A retrospective case-control study.
Victor Alejandro Martinez Pacheco, Sergio Rojas Juarez, Braulio Hernan Velasco Sepulveda, Abel Ramirez Estudillo   +3 more
doaj   +2 more sources

TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

Journal of Nanobiotechnology, 2022
Background Proliferative vitreoretinopathy (PVR) is a blind-causing disease initiated by the activation of retinal pigmented epithelium (RPE) primarily induced by TGF-β families. Migrasome is a recently discovered type of extracellular vesicle related to
Liangjing Wu, Shuai Yang, Hui Li, Yao Zhang, Le Feng, Conghui Zhang, Jiayi Wei, Xunyi Gu, Guotong Xu, Zhaoyang Wang, Fang Wang   +10 more
semanticscholar   +1 more source

EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy

Investigative Ophthalmology and Visual Science, 2022
Purpose Both epidermal growth factor receptor (EGFR) and the Yes-associated protein (YAP) signaling pathway are implicated in cell proliferation and differentiation. In this study, we explored whether the formation of proliferative vitreoretinopathy (PVR)
Wei Zhang, Jing Li
semanticscholar   +1 more source

Novel insights into the pathophysiology of proliferative vitreoretinopathy: The role of vitreoschisis‐induced vitreous cortex remnants

Acta ophthalmologica, 2022
We previously hypothesized a causal relationship between vitreoschisis‐induced vitreous cortex remnants (VCR) and the development of proliferative vitreoretinopathy (PVR).
K. V. van Overdam, T. V. D. van den Bosch, Peter G van Etten, G. Uppal, M. Veckeneer, R. Verdijk   +5 more
semanticscholar   +1 more source

Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development

Journal of Clinical Medicine, 2022
Purpose: To characterize vitreous humor (VH) exosomes and to explore their role in the development of proliferative vitreoretinopathy (PVR) using mass spectrometry-based proteome profiling.
G. K. Nair, Dimitrios Pollalis, J. Wren, Constantin Georgescu, Virginie H. Sjoelund, Sun Young Lee   +5 more
semanticscholar   +1 more source

METTL3 attenuates proliferative vitreoretinopathy and epithelial‐mesenchymal transition of retinal pigment epithelial cells via wnt/β‐catenin pathway

Journal of Cellular and Molecular Medicine, 2021
Proliferative vitreoretinopathy (PVR) is a refractory vitreoretinal fibrosis disease, and epithelial‐mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is the key pathological mechanism of PVR. However, few studies focused on the role
Xinqi Ma, C. Long, Fangyu Wang, Bingsheng Lou, Miner Yuan, Fang Duan, Yao Yang, Jia-qing Li, Xiaobing Qian, Jieting Zeng, Shuibin Lin, Huangxuan Shen, Xiaofeng Lin   +12 more
semanticscholar   +1 more source

Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy

Cell Death and Differentiation, 2021
Proliferative vitreoretinopathy (PVR) is a disease that causes severe blindness and is characterized by the formation of contractile fibrotic subretinal or epiretinal membranes.
Shuai Yang, Hui Li, Haipei Yao, Yao Zhang, H. Bao, Liangjing Wu, Conghui Zhang, Min Li, Le Feng, Jingfa Zhang, Zhi Zheng, Guotong Xu, Fang Wang   +12 more
semanticscholar   +1 more source

Anatomical and Functional Outcomes of Vitrectomy with/without Intravitreal Methotrexate Infusion for Management of Proliferative Vitreoretinopathy Secondary to Rhegmatogenous Retinal Detachment

Journal of Ophthalmology, 2021
Purpose To assess the anatomical and functional outcomes of intravitreal infusion of methotrexate (MTX) during pars plana vitrectomy (PPV) for proliferative vitreoretinopathy (PVR) associated with rhegmatogenous retinal detachment (RRD).
S. E. EL BAHA, M. Leila, Ahmed Amr, Mohamed M A Lolah   +3 more
semanticscholar   +1 more source