Results 21 to 30 of about 389,924 (238)

Proliferative vitreoretinopathy and it’s prevention in cases of extensive penetrating wounds of the sclera

Офтальмохирургия, 2023
Relevance. Currently, there is no single algorithm for the management of patients with extensive penetrating wounds of the sclera, and the frequency of proliferative vitreoretinopathy, leading to adverse outcomes, is very high. Purpose.
S.S. Shamkin, S.N. Subbotina
doaj   +1 more source

Vitrectomy with Silicone Oil Tamponade and Single-Dose Intravitreal Methotrexate for Recurrent Retinal Detachment with Proliferative Vitreoretinopathy

Case Reports in Ophthalmology, 2022
Our case emphasizes the approach of a single-dose of intraoperative methotrexate (MTX) – applied directly into silicone oil – to arrest the anomalous progression of proliferative vitreoretinopathy (PVR).
Adrian Babel, Eric K. Chin, David R.P. Almeida   +2 more
doaj   +1 more source

Experimental Models to Study Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy

International Journal of Molecular Sciences, 2023
Proliferative vitreoretinal diseases (PVDs) encompass proliferative vitreoretinopathy (PVR), epiretinal membranes, and proliferative diabetic retinopathy.
Azine Datlibagi, Anna Zein-El-Din, Maxime Frohly, F. Willermain, C. Delporte, E. Motulsky   +5 more
semanticscholar   +1 more source

Low-Dose Intravitreal Methotrexate for Proliferative Vitreoretinopathy.

Ophthalmic Surgery Lasers and Imaging Retina, 2023
BACKGROUND AND OBJECTIVE Proliferative vitreoretinopathy (PVR) has been mitigated by intravitreal methotrexate (MTX) 400 μg/0.1 mL in several studies. Here, we evaluate the results from a lower dose of MTX, 200 μg/0.05 mL.
Asm S Ullah, C. Toth, H. Burnett, John W. Butler, Jay H Levy, J. D. Benner   +5 more
semanticscholar   +1 more source

TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

Journal of Nanobiotechnology, 2022
Background Proliferative vitreoretinopathy (PVR) is a blind-causing disease initiated by the activation of retinal pigmented epithelium (RPE) primarily induced by TGF-β families. Migrasome is a recently discovered type of extracellular vesicle related to
Liangjing Wu, Shuai Yang, Hui Li, Yao Zhang, Le Feng, Conghui Zhang, Jiayi Wei, Xunyi Gu, Guotong Xu, Zhaoyang Wang, Fang Wang   +10 more
semanticscholar   +1 more source

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy

Investigative Ophthalmology and Visual Science, 2022
Purpose Proliferative vitreoretinopathy (PVR) remains an unresolved clinical challenge and can lead to frequent revision surgery and blindness vision loss.
Yannik Laich, Julian Wolf, R. I. Hajdú, A. Schlecht, Felicitas Bucher, Laurenz J. B. Pauleikhoff, M. Busch, G. Martin, Henrik Faatz, S. Killmer, B. Bengsch, A. Stahl, A. Lommatzsch, G. Schlunck, H. Agostini, S. Boneva, C. Lange   +16 more
semanticscholar   +1 more source

EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy

Investigative Ophthalmology and Visual Science, 2022
Purpose Both epidermal growth factor receptor (EGFR) and the Yes-associated protein (YAP) signaling pathway are implicated in cell proliferation and differentiation. In this study, we explored whether the formation of proliferative vitreoretinopathy (PVR)
Wei Zhang, Jing Li
semanticscholar   +1 more source

Novel insights into the pathophysiology of proliferative vitreoretinopathy: The role of vitreoschisis‐induced vitreous cortex remnants

Acta ophthalmologica, 2022
We previously hypothesized a causal relationship between vitreoschisis‐induced vitreous cortex remnants (VCR) and the development of proliferative vitreoretinopathy (PVR).
K. V. van Overdam, Thierry P P van den Bosch, Peter G van Etten, G. Uppal, M. Veckeneer, R. Verdijk   +5 more
semanticscholar   +1 more source

Infectious necrotizing scleritis and proliferative vitreoretinopathy after scleral buckling in a patient with atopic dermatitis

American Journal of Ophthalmology Case Reports, 2021
Purpose: To report a case of necrotizing scleritis and proliferative vitreoretinopathy due to an acute infection following scleral buckling for the management of rhegmatogenous retinal detachment in a patient with untreated atopic dermatitis ...
Hajime Sakata, Yosuke Harada, Tomona Hiyama, Yoshiaki Kiuchi   +3 more
doaj   +1 more source

Molecular Biologic Milieu in Rhegmatogenous Retinal Detachment and Proliferative Vitreoretinopathy: A Literature Review

Ophthalmic Research, 2022
Multiple lines of evidence support an immunologic response along with inflammation to be implicated in the pathophysiology of primary rhegmatogenous retinal detachment (RRD) and the development of proliferative vitreoretinopathy (PVR).
Konstantinos Ananikas, Panagiotis Stavrakas, C. Kroupis, E. Christou, D. Brouzas, P. Petrou, D. Papakonstantinou   +6 more
semanticscholar   +1 more source