MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou +9 more
wiley +1 more source
Panophthalmitis With Orbital Cellulitis Following Glaucoma Drainage Implant Surgery in an Adult Patient. [PDF]
Alshahwan S +3 more
europepmc +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Peripheral retinal degenerations: multimodal imaging-guided risk stratification and clinical decision-making. [PDF]
Babović S, Maletin N, Denda N.
europepmc +1 more source
Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha +14 more
wiley +1 more source
Using patient input to develop item banks to measure quality-of-life impact of vitreous floaters. [PDF]
Woudstra-de Jong J +5 more
europepmc +1 more source
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale +3 more
wiley +1 more source
A Historical Review of Encircling Laser Retinopexy as a Prophylaxis for Rhegmatogenous Retinal Detachment; and a Commentary on Recent Progress in Stickler Syndrome. [PDF]
Morris RE +6 more
europepmc +1 more source
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren +5 more
wiley +1 more source
Hemolytic Glaucoma Following Intravitreal Aflibercept Injection for Age-Related Macular Degeneration: A Case Report. [PDF]
Sano H, Yanai R, Mitamura Y.
europepmc +1 more source

