Results 141 to 150 of about 4,719,080 (333)

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

Structure of vitreous body and its relationship with liquefaction

open access: yes, 2013
The aim of the study is to clarify the vitreous body structure and liquefaction phenomena. It was found that when melting a frozen rabbit vitreous body, the gel-sol transition phenomenon occurs and the gel structure is broken. This is almost like the
M. Kodama, T. Matsuura, Y. Hara
semanticscholar   +1 more source

Repeat Intraocular Sampling and Microbiological Testing in Infectious Endophthalmitis: A 27‐Year Prospective Observational Study at an Australian Statewide Tertiary Referral Centre

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Endophthalmitis requiring multiple ocular tissue sampling for microbiological testing is uncommon and has not been previously studied. This study aims to analyse cases with at least two ocular tissue samplings and testing of different ocular samples against culture yields. Methods A 27‐year prospective observational study using data
Pravena Kumaran   +5 more
wiley   +1 more source

Trace Elements Iron, Copper and Zinc in Vitreous of Patients with Various Vitreoretinal Diseases

open access: yesIndian Journal of Ophthalmology, 2004
Purpose: To measure the concentrations of iron, copper and zinc in human vitreous and to interpret their levels with various vitreoretinal diseases like proliferative diabetic retinopathy, retinal detachment, intraocular foreign body, Eales′ ...
Sulochana Konerirajapuram   +5 more
doaj  

Current approaches to hemophthalmia treatment. Review

open access: yesOftalʹmologiâ, 2014
Main directions in the treatment of hemophthalmia are appeared: medication, surgical and enzymotherapy (intravitreal enzymatic treatment — IFL, vitrectomy).
D. V. Andgelova
doaj   +1 more source

Expanding the Phenotypic Spectrum Associated With Loss‐of‐Function SMARCA4 Variants to Eye Developmental Anomalies

open access: yesClinical Genetics, EarlyView.
This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau   +7 more
wiley   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

open access: yesCell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava   +9 more
wiley   +1 more source

Vitreous Hemorrhage in Posterior Uveal Melanocytoma: Two Case Reports

open access: yesCase Reports in Ophthalmological Medicine
Conclusion: Melanocytomas are rare, benign melanocytic lesions that resemble nevi. In contrast to optic nerve melanocytoma, those involving the choroid and ciliary body lack specific clinical characteristics.
Lauren B. Yeager   +4 more
doaj   +1 more source

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