Results 121 to 130 of about 69,762 (263)

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Penetrating eye injuries at the workplace : case reports and discussion [PDF]

open access: yes, 2010
We describe two recent cases of penetrating eye injury seen at Mater Dei Hospital, both resulting in a poor final outcome and illustrating the importance of wearing appropriate eye protection at the workplace. In case 1, injury was caused by a metal chip
Agius, Maria, Vella Briffa, Benedict
core  

Bond angle distribution in amorphous germania and silica

open access: yes, 1996
The distribution of Ge-O-Ge and Si-O-Si bond angles alpha in amorphous germania and silica is re-determined on the basis of diffraction experiments.
Liss, K. D., Neuefeind, J.
core   +2 more sources

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Computer-animated model of accommodation and theory of reciprocal zonular action

open access: yesClinical Ophthalmology, 2011
Daniel B Goldberg1,2 1Ophthalmology Department, Drexel College of Medicine, Philadelphia, PA, 2Eye Physicians, Little Silver, NJ, USA Abstract: This report presents a computer-animated model of the structures of accommodation based on new understanding ...
Goldberg DB
doaj  

Are you Buying a Washing Machine? [PDF]

open access: yes, 1936
PDF pages ...
Beall, Thelma, Beard, Ruth
core  

Visual Modelling to Predict Behavioural Responses of Catsharks, Skates, and Plaice to Artificial Light for Use in Bycatch Reduction

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Light can be used to deter bycatch from fishing nets, but few studies have aimed to quantify how species view and respond to light. Here, we used visual models to predict how target (plaice Pleuronectes platessa) and bycatch (small‐spotted catshark Scyliorhinus canicular and undersized skates, Raja spp) species, captured in mixed demersal ...
Jasmine Somerville   +2 more
wiley   +1 more source

Association between continuous glucose monitoring metrics and diabetic retinopathy and albuminuria among Japanese individuals with type 1 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction This study aimed to clarify the relationship between glucose metrics measured by continuous glucose monitoring (CGM) and diabetic retinopathy (DR) and albuminuria among Japanese individuals with type 1 diabetes mellitus. Materials and Methods The study included 294 individuals with type 1 diabetes (68.7% women) who underwent ...
Yuichiro Kondo   +8 more
wiley   +1 more source

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