Results 111 to 120 of about 3,246,007 (207)

PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang   +13 more
wiley   +1 more source

Studies on the vitreous body. II [PDF]

open access: yesBiochemical Journal, 1935
W S, Duke-Elder, H, Davson
openaire   +2 more sources

Thermal Evolution and Optoelectronic Properties of KH2PO4‐Modified Copper–Phosphoric Acid‐Based Geopolymers: A Multifunctional Glass‐Ceramic

open access: yesphysica status solidi (a), Volume 223, Issue 17, 9 September 2026.
XRD/Raman/TGA map phase changes from hydrates to AlPO4–SiO2 solid solutions up to 1000 °C. KH2PO4 improves polymerization and phase control. Combined techniques correlate structure, composition, and optics. Controlled glass‐ceramic forms at 1000 °C with high thermal stability.
Houda Ettoumi   +3 more
wiley   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu   +12 more
wiley   +1 more source

In Vitro Physicochemical and Pharmacokinetic Properties of Bevacizumab Dissolved in Silicone Oils Compared to Hydrogel-Substitutes and Porcine Vitreous Bodies

open access: yesGels
Anti-VEGF agents, e.g., bevacizumab, are used in retinal surgery, while their interaction with silicone oils and novel hydrogels remains unclear. This study examines the in vitro pharmacokinetics of bevacizumab in silicone oil-filled eyes compared to ...
Maximilian Hammer   +10 more
doaj   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui   +9 more
wiley   +1 more source

Visual Blurring Following Posterior Vitreous Detachment in Fuchs Uveitis Syndrome

open access: yesJournal of Ophthalmic & Vision Research
Purpose: To describe the clinical presentation, diagnostic challenges, management, and visual outcome of acute posterior vitreous detachment (PVD) in patients with Fuchs uveitis syndrome (FUS) Methods: This retrospective case series included ...
Alireza Hedayatfar, Soon-Phaik Chee
doaj   +1 more source

FOXO6 inhibits SMURF2‐mediated ubiquitination and degradation of NR4A1 to promote retinal pigment epithelial cell ferroptosis in diabetic retinopathy

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
FOXO6 suppresses the transcriptional expression of SMURF2, thereby limiting the ubiquitination and degradation of NR4A1. Stabilized NR4A1 promotes ferroptosis in RPE cells, contributing to the progression of diabetic retinopathy. Abstract Diabetic retinopathy (DR) is the main cause of vision loss, with retinal pigment epithelial (RPE) cell dysfunction ...
Qiao Chen   +4 more
wiley   +1 more source

Immobilization of High‐Halide Nuclear Waste: A Review of Recent Advances of Relevant Material Design and Processing

open access: yesInternational Journal of Ceramic Engineering &Science, Volume 8, Issue 5, September 2026.
Qualitative comparison on the key properties of various waste form options for the immobilization of high‐halide nuclear waste. ABSTRACT The safe disposal of halide‐containing nuclear wastes is one of the key challenges to address not just for the electrochemical reprocessing of used nuclear fuel, but also for the future implementation of molten salt ...
Jincheng Bai   +2 more
wiley   +1 more source

Cascade‐targeted intervention of the NLRP3 inflammasome and downstream angiogenesis by curcumin nanoparticles for ocular neovascularization therapy

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Ultrasound‐microreactor synthesizes monodisperse 125 nm Cur‐NPs with enhanced solubility. Cur‐NPs suppress VEGF signaling and retinal neovascularization via the NLRP3 axis. Multi‐omics profiling reveals that Cur‐NPs reprogram retinal microglia and metabolic pathways.
Siyu Jiang   +9 more
wiley   +1 more source

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