Results 111 to 120 of about 3,246,007 (207)
PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang +13 more
wiley +1 more source
Studies on the vitreous body. II [PDF]
W S, Duke-Elder, H, Davson
openaire +2 more sources
XRD/Raman/TGA map phase changes from hydrates to AlPO4–SiO2 solid solutions up to 1000 °C. KH2PO4 improves polymerization and phase control. Combined techniques correlate structure, composition, and optics. Controlled glass‐ceramic forms at 1000 °C with high thermal stability.
Houda Ettoumi +3 more
wiley +1 more source
A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu +12 more
wiley +1 more source
Anti-VEGF agents, e.g., bevacizumab, are used in retinal surgery, while their interaction with silicone oils and novel hydrogels remains unclear. This study examines the in vitro pharmacokinetics of bevacizumab in silicone oil-filled eyes compared to ...
Maximilian Hammer +10 more
doaj +1 more source
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui +9 more
wiley +1 more source
Visual Blurring Following Posterior Vitreous Detachment in Fuchs Uveitis Syndrome
Purpose: To describe the clinical presentation, diagnostic challenges, management, and visual outcome of acute posterior vitreous detachment (PVD) in patients with Fuchs uveitis syndrome (FUS) Methods: This retrospective case series included ...
Alireza Hedayatfar, Soon-Phaik Chee
doaj +1 more source
FOXO6 suppresses the transcriptional expression of SMURF2, thereby limiting the ubiquitination and degradation of NR4A1. Stabilized NR4A1 promotes ferroptosis in RPE cells, contributing to the progression of diabetic retinopathy. Abstract Diabetic retinopathy (DR) is the main cause of vision loss, with retinal pigment epithelial (RPE) cell dysfunction ...
Qiao Chen +4 more
wiley +1 more source
Qualitative comparison on the key properties of various waste form options for the immobilization of high‐halide nuclear waste. ABSTRACT The safe disposal of halide‐containing nuclear wastes is one of the key challenges to address not just for the electrochemical reprocessing of used nuclear fuel, but also for the future implementation of molten salt ...
Jincheng Bai +2 more
wiley +1 more source
Ultrasound‐microreactor synthesizes monodisperse 125 nm Cur‐NPs with enhanced solubility. Cur‐NPs suppress VEGF signaling and retinal neovascularization via the NLRP3 axis. Multi‐omics profiling reveals that Cur‐NPs reprogram retinal microglia and metabolic pathways.
Siyu Jiang +9 more
wiley +1 more source

