Results 71 to 80 of about 4,584,652 (321)

Changes in the basis of vitreous body in case of uveitis treated by adalimumab

open access: yesJournal of Ophthalmology, 2015
Objective of the research is to study the dynamics of changes in the basis of vitreous body in case of uveitis treated by Adalimumab. Material and methods. 5 year old patient S.
N.V. Panchenko   +6 more
doaj   +1 more source

Dual‐Crosslinked Betaine‐Based Amphiphilic Hydrogel as a Promising Vitreous Substitute: Anti‐Adhesion, Anti‐Fouling, and Anti‐Cell Proliferation

open access: yesAdvanced Science, EarlyView.
A novel multiple cross‐linked betaine‐type amphiphilic polymer hydrogels are developed via in situ free radical copolymerization. The resultant formation, named P(SBMA‐co‐AANa) hydrogel, functions as a vitreous substitute and demonstrates superior performance in optical properties, support capacity, and biocompatibility on a vitrectomized rabbit model.
Yuting Cai   +8 more
wiley   +1 more source

Overlooked retained intraocular foreign body [PDF]

open access: yesVojnosanitetski Pregled, 2015
Introduction. The most common cause for litigation against ophthalmologists in a trauma case is a missed intraocular foreign body (IOFB). IOFBs cause internal eye damage, but some will come to rest in the posterior segment of the eye.
Adžić-Zečević Antoaneta   +2 more
doaj   +1 more source

Aging and age-related diseases of the ocular lens and vitreous body. [PDF]

open access: yesInvest Ophthalmol Vis Sci, 2013
Reduced quality of life and financial burden due to visual impairment and blindness begin to increase dramatically when individuals reach the age of 40. The major causes of age-related vision loss can be traced to changes to the structure and function of
Petrash JM.
europepmc   +2 more sources

Transthyretin levels in the vitreous correlate with change in visual acuity after vitrectomy [PDF]

open access: yes, 2009
Background/aim: Little is known about biochemical markers related to change in visual acuity after vitrectomy. The potential use of transthyretin (TTR), a carrier of the retinol/retinol-binding protein, as a biochemical marker protein, was investigated ...
De Letter, Els   +7 more
core   +3 more sources

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

open access: yesAdvanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao   +17 more
wiley   +1 more source

Imaging of adult ocular and orbital pathology - a pictorial review [PDF]

open access: yes, 2014
Orbital pathology often presents a diagnostic challenge to the reporting radiologist. The aetiology is protean, and clinical input is therefore often necessary to narrow the differential diagnosis.
Brennan, Paul   +8 more
core   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren   +11 more
wiley   +1 more source

Penetrating eye injuries at the workplace : case reports and discussion [PDF]

open access: yes, 2010
We describe two recent cases of penetrating eye injury seen at Mater Dei Hospital, both resulting in a poor final outcome and illustrating the importance of wearing appropriate eye protection at the workplace. In case 1, injury was caused by a metal chip
Agius, Maria, Vella Briffa, Benedict
core  

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

open access: yesAdvanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong   +9 more
wiley   +1 more source

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