Results 131 to 140 of about 3,092 (233)

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Replacing the vitreous body with hydrogels: Rationale and strategies. [PDF]

Prog Retin Eye Res
Schulz A, Keskar M, Swindle-Reilly KE, Junge V, Parikh BH, Su X, Liu Z, Seah I.   +7 more
europepmc   +1 more source

Stimuli‐Responsive Hydrogels for Optical Applications: Mechanisms, Architectures, and Translational Challenges

Aggregate, Volume 7, Issue 6, June 2026.
The review discusses stimuli‐responsive hydrogels as soft optical materials that translate physical, chemical, and biological cues into refractive‐index, scattering, birefringence, diffraction, and transparency changes. It examines major stimulus classes and photonic architectures for biosensing, waveguiding, adaptive lenses, smart windows, and therapy.
Andrés Bernal‐Ballén, Alexandr Dejneka, Oleg Lunov   +2 more
wiley   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source

Peripheral retinal degenerations: multimodal imaging-guided risk stratification and clinical decision-making. [PDF]

Front Ophthalmol (Lausanne)
Babović S, Maletin N, Denda N.
europepmc   +1 more source

Nanorobotic platforms for targeted drug delivery: Materials engineering, functional dynamics, and biomedical translation

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Graphical representation of nanorobotic platforms for targeted drug delivery. Abstract Background Nanorobotic systems represent an emerging and disruptive paradigm in nanomedicine for precision drug delivery, controlled therapeutic release, and minimally invasive biomedical interventions.
Mohd Shoab Ali, Garima Gupta, Khang Wen Goh, Rahul Shukla, Amirhossein Sahebkar, Prashant Kesharwani   +5 more
wiley   +1 more source

From fibrotic mechanisms to clinical translation: the drug therapy revolution and delivery system breakthrough in proliferative vitreoretinopathy. [PDF]

Front Immunol
Chen Z, Liu J, Quan L, Wu L, Xu Q.
europepmc   +1 more source

Competent Non‐Native Alternative Host Reduces Infection Success in a Generalist Parasite

Ecology and Evolution, Volume 16, Issue 6, June 2026.
In this study, we experimentally assessed how the addition of a non‐native alternative host affects the infection success of the larval generalist trematode, Diplostomum pseudospathaceum, in fish intermediate hosts. Our results demonstrate that the presence of alternative hosts, especially the non‐native ones, can reduce parasite transmission through ...
Markéta Ondračková, Lukáš Vetešník, Veronika Bartáková, Michal Janáč   +3 more
wiley   +1 more source

Tailoring polymethylhydrosiloxane as candidate material for vitreous humour substitution: physical properties and in vitro toxicity. [PDF]

BMC Chem
Auliya DG, Arini VF, Nurmadanti T, Fauziah U, Setiadji S, Fitrilawati F, Risdiana R.   +6 more
europepmc   +1 more source

DualPath‐DRNet: A Self‐Annotating Dual‐Path Networks for End‐To‐End Diabetic Retinopathy Diagnosis

Engineering Reports, Volume 8, Issue 6, June 2026.
DualPath‐DRNet for automated diabetic retinopathy diagnosis and grading. ABSTRACT One of the challenges in detecting Diabetic Retinopathy (DR) is the detection of subtle early‐stage microaneurysms. DualPath‐DRNet is an end‐to‐end deep learning pipeline for 5‐class DR prediction. The novelty of this method lies in combining lesion detection using YOLOv8,
Ankur Chaudhary, Neetu Faujdar, Ghanshyam Singh   +2 more
wiley   +1 more source