Results 161 to 170 of about 53,616 (262)

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding   +6 more
wiley   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

open access: yesMedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu   +5 more
wiley   +1 more source

Modelling of a Gas Cap Gas Lift System [PDF]

open access: yes, 2011
Imperial Users ...
Okenwa, Junior Chukwudi   +1 more
core  

114 VLPs and particle vaccines

open access: yesJAIDS Journal of Acquired Immune Deficiency Syndromes, 2014
VLPs represent a powerful tool for vaccine development, representing the closest strategy to the native viruses for displaying and delivering conformational epitopes, with improved induction of antibodies and immune response in its whole. Moreover, the lack of genetic material makes VLPs the “safer counterpart” of live attenuated or killed viral ...
openaire   +2 more sources

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

open access: yesNano Select, Volume 7, Issue 2, February 2026.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani   +3 more
wiley   +1 more source

VLP Extraction from Fecal Samples v2

open access: yes, 2021
This protocol is for isolation of bacteriophages from fecal matter. It is based on the protocol used for the COPSAC10 cohort and was originally described by Ling Deng in doi:10.3390/v11070667. Extraction is performed using centrifugation and ultrafiltration to isolate viral particles and get rid of contaminants.
openaire   +1 more source

Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment

open access: yesSmartMat, Volume 7, Issue 1, February 2026.
Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova   +8 more
wiley   +1 more source

Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing

open access: yesMicrobiology Spectrum
Due to varying sequencing strategies, current gut virome findings show significant variability. Specifically, bulk- and virus-like particle (VLP)-enriched metagenomic sequencing (termed bulk and VLP, respectively) present unique advantages and ...
Yun Li   +6 more
doaj   +1 more source

An Explicit Test of Kill the Winner: Protistan Grazing and Phage Lysis Differentially Impact Fast‐Growing Bacterial Taxa in the Coastal Antarctic

open access: yesEnvironmental Microbiology, Volume 28, Issue 2, February 2026.
We evaluated whether predators ‘kill the winner’ wherein protists and phages preferentially impact the most abundant members of bacterial assemblages over an austral summer with weekly dilution experiments. Seawater from 10 m was divided into two serial dilutions with either 0.2 μm (to evaluate protist grazing) or 30 kDa (to evaluate protist grazing ...
Elizabeth Connors   +4 more
wiley   +1 more source

Surgical Treatment of Distal Radius Fractures Using Minimally Invasive Plate Osteosynthesis or Open Reduction and Internal Fixation: A Five-Year Comparative Follow-Up Study

open access: yesApplied Sciences
Distal radius fractures (DRFs) constitute one of the most prevalent injuries in adults. This study compares the clinical and radiological outcomes of intra- and extra-articular DRFs treated with percutaneous Kirschner wires (PKW) or volar locking plates (
Giuseppe Rovere   +8 more
doaj   +1 more source

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