Results 1 to 10 of about 6,680,139 (200)

Programmable polymorphism of a virus-like particle [PDF]

Communications Materials, 2022
Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape
Artur P. Biela, Antonina Naskalska, Farzad Fatehi, Reidun Twarock, Jonathan G. Heddle   +4 more
doaj   +6 more sources

Special Issue “Virus-Like Particle Vaccines” [PDF]

Viruses, 2020
Virus-like particles (VLPs) have become a key tool for vaccine developers and manufacturers [...]
Monique Vogel, Martin F. Bachmann
doaj   +3 more sources

A Virus-Like Particle-Based Vaccine Candidate against the Tick-Borne Powassan Virus Induces Neutralizing Antibodies in a Mouse Model

Pathogens, 2021
Powassan virus (POWV) is a tick-borne flavivirus circulating in North America and the Russian Far East that can cause severe neuroinvasive diseases, including encephalitis, meningitis, and meningoencephalitis.
Velasco Cimica, Sahar Saleem, Emily Matuczinski, Debra Adams-Fish, Conor McMahon, Sujatha Rashid, Timothy T. Stedman   +6 more
doaj   +3 more sources

Development of a vaccine based on mRNA assembly of PEDV virus-like particle [PDF]

Journal of Virology
Porcine epidemic diarrhea virus (PEDV) represents a highly contagious enteropathogenic coronavirus affecting swine. This virus elicits acute diarrhea in neonatal nursing piglets, with mortality approaching 100%, and, thus, imposes enormous economic ...
Mengdi Yang, Yongxiang Zhao, Weilu Guo, Lizhong Wang, Xu Song, Xinmei Geng, Shiyu Liu, Hongqi Shang, Mi Hu, Shanshan Yang, Yunchuan Li, Min Sun, Lixiang Zhao, Tianyi Zhong, Bin Li, Baochao Fan   +15 more
doaj   +2 more sources

Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]

Vaccines
Poliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han, Jinbo Xiao, Shiyao Zhang, Tongyue Su, Yinuo Liu, Yong Zhang   +5 more
doaj   +2 more sources

Preclinical Development of a Novel Zika Virus-like Particle Vaccine in Combination with Tetravalent Dengue Virus-like Particle Vaccines [PDF]

Vaccines
Declared as a Public Health Emergency in 2016 by the World Health Organization (WHO), the Zika virus (ZIKV) continues to cause outbreaks that are linked to increased neurological complications.
Dominik A. Rothen, Sudip Kumar Dutta, Pascal S. Krenger, Alessandro Pardini, Anne-Cathrine S. Vogt, Romano Josi, Ilva Lieknina, Albert D. M. E. Osterhaus, Mona O. Mohsen, Monique Vogel, Byron Martina, Kaspars Tars, Martin F. Bachmann   +12 more
doaj   +2 more sources

Zika virus-like particle (VLP) based vaccine. [PDF]

PLoS Neglected Tropical Diseases, 2017
The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders.
Hélène Boigard, Alexandra Alimova, George R Martin, Al Katz, Paul Gottlieb, Jose M Galarza   +5 more
doaj   +1 more source

Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes

Vaccines, 2023
New vaccine delivery technologies, such as mRNA, have played a critical role in the rapid and efficient control of SARS-CoV-2, helping to end the COVID-19 pandemic.
Yongping Yang, Wing-Pui Kong, Cuiping Liu, Tracy J. Ruckwardt, Yaroslav Tsybovsky, Lingshu Wang, Shuishu Wang, Daniel W. Biner, Man Chen, Tracy Liu, Jonah Merriam, Adam S. Olia, Li Ou, Qi Qiu, Wei Shi, Tyler Stephens, Eun Sung Yang, Baoshan Zhang, Yi Zhang, Qiong Zhou, Reda Rawi, Richard A. Koup, John R. Mascola, Peter D. Kwong   +23 more
doaj   +1 more source

Development of Respiratory Syncytial Virus Vaccine Candidates for the Elderly

Viruses, 2023
Respiratory syncytial virus (RSV) is a significant threat to elderly populations and repeated infections that occur throughout life are poorly protective. To assess the role of prior RSV infections as well as elderly immune senescence on vaccine efficacy,
Jorge C. G. Blanco, Lori M. Cullen, Arash Kamali, Fatouomata Y. D. Sylla, Marina S. Boukhvalova, Trudy G. Morrison   +5 more
doaj   +1 more source

Cross-Protection Induced by Virus-like Particles Derived from the Influenza B Virus

Biomedicines, 2022
The mismatch between the circulating influenza B virus (IBV) and the vaccine strain contributes to the rapid emergence of IBV infection cases throughout the globe, which necessitates the development of effective vaccines conferring broad protection. Here,
Hae-Ji Kang, Ki-Back Chu, Keon-Woong Yoon, Gi-Deok Eom, Jie Mao, Fu-Shi Quan   +5 more
doaj   +1 more source