Programmable polymorphism of a virus-like particle [PDF]
Communications Materials, 2022 Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape
Artur P. Biela +4 more
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Special Issue “Virus-Like Particle Vaccines” [PDF]
Viruses, 2020 Virus-like particles (VLPs) have become a key tool for vaccine developers and manufacturers [...]
Monique Vogel, Martin F. Bachmann
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Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]
VaccinesPoliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han +5 more
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Development of a vaccine based on mRNA assembly of PEDV virus-like particle [PDF]
Journal of VirologyPorcine epidemic diarrhea virus (PEDV) represents a highly contagious enteropathogenic coronavirus affecting swine. This virus elicits acute diarrhea in neonatal nursing piglets, with mortality approaching 100%, and, thus, imposes enormous economic ...
Mengdi Yang +15 more
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Preclinical Development of a Novel Zika Virus-like Particle Vaccine in Combination with Tetravalent Dengue Virus-like Particle Vaccines [PDF]
VaccinesDeclared as a Public Health Emergency in 2016 by the World Health Organization (WHO), the Zika virus (ZIKV) continues to cause outbreaks that are linked to increased neurological complications.
Dominik A. Rothen +12 more
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Human Vaccines & Immunotherapeutics, 2017 Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (
Hye Suk Hwang +10 more
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Four nudivirus core genes present in the genome of Venturia canescens are required for virus-like particle formation and prevention of encapsulation of parasitoid wasp eggs [PDF]
Journal of VirologyVenturia canescens is a parasitoid wasp that harbors a domesticated endogenous virus (DEV) and parasitizes host insects like Ephestia kuehniella. The V. canescens DEV evolved from an alphanudivirus and produces virus-like particles (VLPs) in females that
Meng Mao +4 more
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A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis [PDF]
International Journal of Nanomedicine, 2012 Wei Shao1, Arghya Paul1, Sana Abbasi1, Parminder S Chahal2, Jimmy A Mena2, Johnny Montes2, Amine Kamen2, Satya Prakash11Biomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering and Artificial Cells and Organs ...
Shao W +7 more
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Zika virus-like particle (VLP) based vaccine. [PDF]
PLoS Neglected Tropical Diseases, 2017 The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders.
Hélène Boigard +5 more
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Vaccines, 2023 New vaccine delivery technologies, such as mRNA, have played a critical role in the rapid and efficient control of SARS-CoV-2, helping to end the COVID-19 pandemic.
Yongping Yang +23 more
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