Results 11 to 20 of about 233,564 (300)

Programmable polymorphism of a virus-like particle [PDF]

open access: yesCommunications Materials, 2022
Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape
Artur P. Biela   +4 more
doaj   +6 more sources

Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]

open access: yesVaccines
Poliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han   +5 more
doaj   +2 more sources

Preclinical Development of a Novel Zika Virus-like Particle Vaccine in Combination with Tetravalent Dengue Virus-like Particle Vaccines [PDF]

open access: yesVaccines
Declared as a Public Health Emergency in 2016 by the World Health Organization (WHO), the Zika virus (ZIKV) continues to cause outbreaks that are linked to increased neurological complications.
Dominik A. Rothen   +12 more
doaj   +2 more sources

Development of a vaccine based on mRNA assembly of PEDV virus-like particle [PDF]

open access: yesJournal of Virology
Porcine epidemic diarrhea virus (PEDV) represents a highly contagious enteropathogenic coronavirus affecting swine. This virus elicits acute diarrhea in neonatal nursing piglets, with mortality approaching 100%, and, thus, imposes enormous economic ...
Mengdi Yang   +15 more
doaj   +2 more sources

Virus-like particle vaccines containing F or F and G proteins confer protection against respiratory syncytial virus without pulmonary inflammation in cotton rats

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (
Hye Suk Hwang   +10 more
doaj   +2 more sources

Four nudivirus core genes present in the genome of Venturia canescens are required for virus-like particle formation and prevention of encapsulation of parasitoid wasp eggs [PDF]

open access: yesJournal of Virology
Venturia canescens is a parasitoid wasp that harbors a domesticated endogenous virus (DEV) and parasitizes host insects like Ephestia kuehniella. The V. canescens DEV evolved from an alphanudivirus and produces virus-like particles (VLPs) in females that
Meng Mao   +4 more
doaj   +2 more sources

Virus-like particle vaccines: immunology and formulation for clinical translation

open access: yesExpert Review of Vaccines, 2018
Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation from laboratory models, to routine clinical administration. While some VLP vaccines thrive and are readily adopted into the vaccination schedule, others are
Braeden Donaldson   +4 more
doaj   +2 more sources

Zika virus-like particle (VLP) based vaccine. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders.
Hélène Boigard   +5 more
doaj   +1 more source

Special Issue “Virus-Like Particle Vaccines”

open access: yesViruses, 2020
Virus-like particles (VLPs) have become a key tool for vaccine developers and manufacturers [...]
Monique Vogel, Martin F. Bachmann
doaj   +1 more source

Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes

open access: yesVaccines, 2023
New vaccine delivery technologies, such as mRNA, have played a critical role in the rapid and efficient control of SARS-CoV-2, helping to end the COVID-19 pandemic.
Yongping Yang   +23 more
doaj   +1 more source

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