Results 21 to 30 of about 6,680,139 (200)

A Novel Recombinant Virus-Like Particles Displaying B and T Cell Epitopes of Japanese Encephalitis Virus Offers Protective Immunity in Mice and Guinea Pigs

Vaccines, 2021
Virus-like particles (VLPs) are non-replicative vectors for the delivery of heterologous epitopes and are considered one of the most potent inducers of cellular and humoral immune responses in mice and guinea pigs.
Muhammad Naveed Anwar, Chunying Jiang, Di Di, Junjie Zhang, Shuang Guo, Xin Wang, Muddassar Hameed, Abdul Wahaab, Donghua Shao, Zongjie Li, Ke Liu, Beibei Li, Yafeng Qiu, Zhiyong Ma, Jianchao Wei   +14 more
doaj   +1 more source

Virus-Like Particle Production in Atmospheric Eubacteria Isolates

Atmosphere, 2019
Culturable eubacterial isolates were collected at various altitudes in Earth’s atmosphere, including ~1.5 m above ground in Tallahassee, FL, USA; ~10.0 m above sea level over the mid-Atlantic ridge (~15° N); ~20 km above ground over the ...
Nuria Teigell-Perez, Cristina Gonzalez-Martin, Basilio Valladares, David J. Smith, Dale W. Griffin   +4 more
doaj   +1 more source

Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1

Frontiers in Immunology, 2018
It is acknowledged that vaccines remain the best hope for eliminating the HIV-1 epidemic. However, the failure to produce effective vaccine immunogens and the inability of conventional delivery strategies to elicit the desired immune responses remains a ...
Yong Gao, Chanuka Wijewardhana, Jamie F. S. Mann   +2 more
doaj   +1 more source

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Kien, F., Nicholls, JM, Bruzzone, R, Chan, C. M., Tsao, SW, Kien, F, Siu, Y. L., Escriou, N, Altmeyer, R., Nal, B., Nicholls, J. M., Chan, CM, Siu, YL, Lo, J, Peiris, J. S. M., Tsao, S. W., Teoh, KT, Nal, B, Teoh, K. T., Peiris, JSM, Altmeyer, R, Lo, J., Escriou, N., Bruzzone, R.   +23 more
core   +1 more source

Construction and characterization of chimaeric human immunodefiency virus type 1 subtype C Gag virus-like particles [PDF]

, 2006
Includes bibliographical references (leaves 114-128).In this study I explored the possibility of making HIV-1 subtype C Pr55gag-based chimaeric virus-like particles (VLPs) as a boost to the HIV-IC multigene DNA vaccine pTHr.grttnC, which encodes a ...
Halsey, Richard James
core   +1 more source

Tomato marchitez virus, a new plant picorna-like virus from tomato related to tomato torrado virus [PDF]

, 2008
A new virus was isolated from a tomato plant from the state of Sinaloa in Mexico. This plant showed symptoms locally known as `marchitez disease¿: severe leaf necrosis, beginning at the base of the leaflets, and necrotic rings on the fruits.
Verbeek, M., Dullemans, A.M., Heuvel, J.F.J.M., van den, Maris, P.C., Vlugt, R.A.A., van der   +4 more
core   +1 more source

Virus-like particle vaccine protects against 2009 H1N1 pandemic influenza virus in mice. [PDF]

PLoS ONE, 2010
The 2009 influenza pandemic and shortages in vaccine supplies worldwide underscore the need for new approaches to develop more effective vaccines.We generated influenza virus-like particles (VLPs) containing proteins derived from the A/California/04/2009
Fu-Shi Quan, Aswani Vunnava, Richard W Compans, Sang-Moo Kang   +3 more
doaj   +1 more source

Cryotomography of budding influenza a virus reveals filaments with diverse morphologies that mostly do not bear a genome at their distal end [PDF]

, 2013
Influenza viruses exhibit striking variations in particle morphology between strains. Clinical isolates of influenza A virus have been shown to produce long filamentous particles while laboratory-adapted strains are predominantly spherical.
Swetha Vijayakrishnan, Vijayakrishnan Swetha, Jackson David, Worawit Suphamungmee, David Bhella, Loney Colin, Bhella, D., Swetha Vijayakrishnan (418947), Colin Loney (418948), David Jackson (84936), Frazer J. Rixon (129686), Colin Loney, Suphamungmee Worawit, Rixon, F.J., Jackson, David, Worawit Suphamungmee (418949), Rixon Frazer J., Vijayakrishnan, Swetha, Rixon, Frazer J., Loney, Colin, Bhella David, David Jackson, Loney, C., Suphamungmee, W., Jackson, D., Bhella, David, Vijayakrishnan, S., David Bhella (129684), Suphamungmee, Worawit, Frazer J Rixon   +29 more
core   +1 more source

Optimization of chimaeric HIV-1 virus-like particle (VLP) production and immunogenicity testing of VLPs in mice [PDF]

, 2008
Includes abstract.Includes bibliographical references (leaves 139-148).The devastating effect the HIV pandemic has had on the human population in the last twenty five years has highlighted the great need to develop a prophylactic HIV vaccine.
Pillay, Sirika
core   +1 more source

Escherichia coli-derived virus-like particles in vaccine development

npj Vaccines, 2017
Recombinant virus-like particle-based vaccines are composed of viral structural proteins and mimic authentic native viruses but are devoid of viral genetic materials. They are the active components in highly safe and effective vaccines for the prevention
Xiaofen Huang, Xin Wang, Jun Zhang, Ningshao Xia, Qinjian Zhao   +4 more
doaj   +1 more source