Results 31 to 40 of about 231,821 (301)
A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]
, 2016 A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul +13 more
core +2 more sources
Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1
Frontiers in Immunology, 2018 It is acknowledged that vaccines remain the best hope for eliminating the HIV-1 epidemic. However, the failure to produce effective vaccine immunogens and the inability of conventional delivery strategies to elicit the desired immune responses remains a ...
Yong Gao +2 more
doaj +1 more source
Norwalk virus-like particles as vaccines [PDF]
Expert Review of Vaccines, 2010 Noroviruses (NoV) cause the great majority of epidemic nonbacterial gastroenteritis in humans. Expression of the capsid protein in recombinant systems, including insect and plant cells, yields assembly of virus-like particles (VLPs) that mimic the antigenic structure of authentic virions, and are relatively acid- and heat-stable.
Melissa, Herbst-Kralovetz +2 more
openaire +2 more sources
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
, 2012 Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Corey W. Hecksel +6 more
core +7 more sources
The 5th virus-like particle and nano-particle vaccines (VLPNPV) conference
Expert Review of Vaccines, 2019 Virus-like particles (VLPs) and nano-particles (NPs) are promising vaccine platforms that have led to the successful development of commercially available vaccines.
Paul Engeroff, Martin F. Bachmann
doaj +1 more source
Virus-like particle vaccine protects against 2009 H1N1 pandemic influenza virus in mice. [PDF]
PLoS ONE, 2010 The 2009 influenza pandemic and shortages in vaccine supplies worldwide underscore the need for new approaches to develop more effective vaccines.We generated influenza virus-like particles (VLPs) containing proteins derived from the A/California/04/2009
Fu-Shi Quan +3 more
doaj +1 more source
Escherichia coli-derived virus-like particles in vaccine development
npj Vaccines, 2017 Recombinant virus-like particle-based vaccines are composed of viral structural proteins and mimic authentic native viruses but are devoid of viral genetic materials. They are the active components in highly safe and effective vaccines for the prevention
Xiaofen Huang +4 more
doaj +1 more source
Influenza virus morphogenesis and budding. [PDF]
, 2009 Influenza viruses are enveloped, negative stranded, segmented RNA viruses belonging to Orthomyxoviridae family. Each virion consists of three major sub-viral components, namely (i) a viral envelope decorated with three transmembrane proteins ...
Balogun, Rilwan A +4 more
core +1 more source
N-terminally myristoylated feline foamy virus Gag allows Env-independent budding of sub-viral particles [PDF]
, 2011 Foamy viruses (FVs) are distinct retroviruses classified as Spumaretrovirinae in contrast to the other retroviruses, the Orthoretrovirinae. As a unique feature of FVs, Gag is not sufficient for sub-viral particle (SVP) release. In primate and feline FVs (
Liu, Yang +2 more
core +2 more sources
Bionanomaterials from plant viruses [PDF]
, 2015 Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
core +2 more sources