Results 31 to 40 of about 6,988,155 (300)

Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1

Frontiers in Immunology, 2018
It is acknowledged that vaccines remain the best hope for eliminating the HIV-1 epidemic. However, the failure to produce effective vaccine immunogens and the inability of conventional delivery strategies to elicit the desired immune responses remains a ...
Yong Gao, Chanuka Wijewardhana, Jamie F. S. Mann   +2 more
doaj   +1 more source

A Virus-Like Particle-Based Vaccine Candidate against the Tick-Borne Powassan Virus Induces Neutralizing Antibodies in a Mouse Model

Pathogens, 2021
Powassan virus (POWV) is a tick-borne flavivirus circulating in North America and the Russian Far East that can cause severe neuroinvasive diseases, including encephalitis, meningitis, and meningoencephalitis.
Velasco Cimica, Sahar Saleem, Emily Matuczinski, Debra Adams-Fish, Conor McMahon, Sujatha Rashid, Timothy T. Stedman   +6 more
doaj   +1 more source

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]

, 2013
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A., Christelle Yeromonahos (413081), Juha T. Huiskonen (191734), David Bitto, David Bitto (413079), Bowden, Thomas A, Elliott, Richard M., Richard M. Elliott (252934), Elliott, Richard, Bowden Thomas A., Yeromonahos, Christelle, Huiskonen, Juha T., Angela McLees (413080), Elliott, Richard M, Christelle Yeromonahos, Pierson, Ted, Huiskonen, J.T., Elliott, R.M., Huiskonen, Juha, Richard M Elliott, McLees, Angela, Bowden, T.A., Bitto, David, Bitto David, Huiskonen, Juha T, Elliott Richard M., Bowden, Thomas A., Thomas A. Bowden (413078), McLees Angela, Bitto, D., Bowden, Thomas, Huiskonen Juha T., Angela McLees, Yeromonahos, C., Thomas A Bowden, Yeromonahos Christelle, Juha T Huiskonen   +36 more
core   +1 more source

Construction and characterization of chimaeric human immunodefiency virus type 1 subtype C Gag virus-like particles [PDF]

, 2006
Includes bibliographical references (leaves 114-128).In this study I explored the possibility of making HIV-1 subtype C Pr55gag-based chimaeric virus-like particles (VLPs) as a boost to the HIV-IC multigene DNA vaccine pTHr.grttnC, which encodes a ...
Halsey, Richard James
core   +1 more source

The impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a mechanistic computational model approach -- Code in Matlab

, 2023
<p>This is the code for paper "The impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a mechanistic computational model approach"</p ...
Liu, Xiao, Stahelin, Robert, Pienaar, Elsje   +2 more
core   +1 more source

Plant production and immunogenic characterisation of Human papillomavirus chimaeric vaccines [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 153-175).Cervical cancer is primarily caused by infection with Human papillomavirus (HPV) and is a global concern, particularly in developing countries which contain ~80% of the cervical ...
Pineo, Catherine
core   +1 more source

Escherichia coli-derived virus-like particles in vaccine development

npj Vaccines, 2017
Recombinant virus-like particle-based vaccines are composed of viral structural proteins and mimic authentic native viruses but are devoid of viral genetic materials. They are the active components in highly safe and effective vaccines for the prevention
Xiaofen Huang, Xin Wang, Jun Zhang, Ningshao Xia, Qinjian Zhao   +4 more
doaj   +1 more source

Virus-like particle vaccine protects against 2009 H1N1 pandemic influenza virus in mice. [PDF]

PLoS ONE, 2010
The 2009 influenza pandemic and shortages in vaccine supplies worldwide underscore the need for new approaches to develop more effective vaccines.We generated influenza virus-like particles (VLPs) containing proteins derived from the A/California/04/2009
Fu-Shi Quan, Aswani Vunnava, Richard W Compans, Sang-Moo Kang   +3 more
doaj   +1 more source

Hepatitis B Virus (HBV) Subviral Particles as Protective Vaccines and Vaccine Platforms

Viruses, 2020
Hepatitis B remains one of the major global health problems more than 40 years after the identification of human hepatitis B virus (HBV) as the causative agent.
Joan Kha-Tu Ho, Beena Jeevan-Raj, Hans-Jürgen Netter   +2 more
doaj   +1 more source

The structural basis for the integrity of adenovirus Ad3 dodecahedron [PDF]

, 2012
During the viral life cycle adenoviruses produce excess capsid proteins. Human adenovirus serotype 3 (Ad3) synthesizes predominantly an excess of free pentons, the complexes of pentameric penton base and trimeric fiber proteins, which are responsible for
Fender, Pascal, Monika Zochowska (134637), Jean-Pierre Andrieu, Ewa Szolajska (134629), Stephen Cusack (134664), Burmeister, Wim P, Pascal Fender (132764), Szolajska, Ewa, Pascal Fender, Nerlo, Barbara, Burmeister, Wim P., Igor Andreev, Wim P. Burmeister (134634), Wim P Burmeister, Guy Schoehn, Jadwiga Chroboczek (134668), Andreev, Igor, Naskalska, Antonina, Stephen Cusack, Chroboczek, Jadwiga, Barbara Nerlo (134643), Ewa Szolajska, Chloe Zubieta (134662), Barbara Nerlo, Igor Andreev (134649), Andrieu, Jean-Pierre, Jadwiga Chroboczek, Chloe Zubieta, Monika Zochowska, Zochowska, Monika, Cusack, Stephen, Jean-Pierre Andrieu (134655), Schoehn, Guy, Antonina Naskalska, Guy Schoehn (27525), Zubieta, Chloe, Antonina Naskalska (134660), Burmeister Wim P., Chroboczek Jadwiga, Andrieu Jean-Pierre, Szolajska Ewa, Cusack Stephen, Andreev Igor, Schoehn Guy, Naskalska Antonina, Zubieta Chloe, Nerlo Barbara, Zochowska Monika, Fender Pascal   +48 more
core   +3 more sources