Results 31 to 40 of about 6,680,139 (200)

Multiplex Human Papillomavirus L1L2 virus-like particle antibody binding assay

MethodsX, 2022
A variety of in vitro techniques are available to estimate the level of antibodies present in human serum samples. Such tests are highly specific and are used to determine prior exposure to a pathogen or to estimate the magnitude, breadth and durability ...
Kavita Panwar, Anna Godi, Clementina E. Cocuzza, Nick Andrews, Jo Southern, Paul Turner, Elizabeth Miller, Simon Beddows   +7 more
doaj   +1 more source

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells [PDF]

, 2013
Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health.
McGivern, David R., Fengyu Hu, Daisuke Yamane (206804), David R McGivern, Hu, Fengyu, Hiromichi Dansako (357935), Nobuyuki Kato (235685), Christoph Welsch (22852), Stanley M. Lemon (30543), Daisuke Yamane, Christoph Welsch, Welsch, Christoph, David R. McGivern (415119), Lemon, Stanley M., Kato, Nobuyuki, Fengyu Hu (415120), Dansako, Hiromichi, Stanley M Lemon, Yamane, Daisuke, Nobuyuki Kato, Hiromichi Dansako   +20 more
core   +1 more source

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]

, 2013
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A., Huiskonen, JT, Yeromonahos, C, Christelle Yeromonahos (413081), Juha T. Huiskonen (191734), David Bitto, David Bitto (413079), Bowden, Thomas A, Elliott, RM, Elliott, Richard M., Richard M. Elliott (252934), Elliott, Richard, Bowden Thomas A., McLees, A, Yeromonahos, Christelle, Huiskonen, Juha T., Angela McLees (413080), Elliott, Richard M, Christelle Yeromonahos, Pierson, Ted, Huiskonen, J.T., Elliott, R.M., Huiskonen, Juha, Richard M Elliott, McLees, Angela, Bowden, T.A., Bitto, David, Bitto David, Bitto, D, Huiskonen, Juha T, Elliott Richard M., Bowden, Thomas A., Thomas A. Bowden (413078), McLees Angela, Bitto, D., Bowden, Thomas, Huiskonen Juha T., Angela McLees, Bowden, TA, Yeromonahos, C., Thomas A Bowden, Yeromonahos Christelle, Juha T Huiskonen   +42 more
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Plant production and immunogenic characterisation of Human papillomavirus chimaeric vaccines [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 153-175).Cervical cancer is primarily caused by infection with Human papillomavirus (HPV) and is a global concern, particularly in developing countries which contain ~80% of the cervical ...
Pineo, Catherine
core   +1 more source

Bioanalytics for Influenza Virus-Like Particle Characterization and Process Monitoring

Frontiers in Bioengineering and Biotechnology, 2022
Virus-like particles (VLPs) are excellent platforms for the development of influenza vaccine candidates. Nonetheless, their characterization is challenging due to VLPs’ unique biophysical and biochemical properties. To cope with such complexity, multiple
Sofia B. Carvalho, Sofia B. Carvalho, Ricardo J. S. Silva, Ricardo J. S. Silva, Marcos F. Q. Sousa, Marcos F. Q. Sousa, Cristina Peixoto, Cristina Peixoto, António Roldão, António Roldão, Manuel J. T. Carrondo, Paula M. Alves, Paula M. Alves   +12 more
doaj   +1 more source

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity [PDF]

, 2013
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with ...
Owens, Ray, Paramasivam, S, Kotecha, A, Wilsden, G, Parida, Satya, Paton, David, Ren, Junyuan, Al-Khalil, Tara, Belsham, Graham J., Lomonossoff, GP, Li, Yanmin, Belsham, GJ, Loureiro, S, Kotecha, Abhay, Belsham, Graham, Owens, R, Stuart, David I, Lomonossoff, George P., Porta, C, Xu, X, Parida, S, Lomonossoff, George P, Burman, Alison, Paton, D, Jones, IM, Curry, S, Blesham, Graham J., Paramasivam, Saravanan, Xu, Xiaodong, Stuart, DI, Charleston, Bryan, Jackson, T, Charleston, B, Burman, A, Jones, Ian M., Porta, Claudine, Ren, J, Stuart, David I., Fry, E, Stuart, David, Jones, Ian M, Ferris, N, Ferris, Nigel, Loureiro, Silvia, Belsham, Graham J, Curry, Stephen, Jackson, Terry, Al-Khalil, T, Li, Y, Fry, Elizabeth, Wilsden, Ginette   +50 more
core   +1 more source

Hepatitis B Virus (HBV) Subviral Particles as Protective Vaccines and Vaccine Platforms

Viruses, 2020
Hepatitis B remains one of the major global health problems more than 40 years after the identification of human hepatitis B virus (HBV) as the causative agent.
Joan Kha-Tu Ho, Beena Jeevan-Raj, Hans-Jürgen Netter   +2 more
doaj   +1 more source

Activation of the beta interferon promoter by paramyxoviruses in the absence of virus protein synthesis [PDF]

, 2012
Conflicting reports exist regarding the requirement for virus replication in interferon (IFN) induction by paramyxoviruses. Our previous work has demonstrated that pathogen-associated molecular patterns capable of activating the IFN-induction cascade are
Killip, M. J., Randall, RE, Goodbourn, S., Precious, BL, Young, D. F., Precious, B. L., Randall, R. E., S. Goodbourn, Goodbourn, S, D. F. Young, R. E. Randall, M. J. Killip, Young, DF, Killip, MJ, B. L. Precious   +14 more
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Virus-like particle vaccines containing F or F and G proteins confer protection against respiratory syncytial virus without pulmonary inflammation in cotton rats

Human Vaccines & Immunotherapeutics, 2017
Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (
Hye Suk Hwang, Ki-Hye Kim, Youri Lee, Young-Tae Lee, Eun-Ju Ko, SooJin Park, Jong Seok Lee, Byung-cheol Lee, Young-Man Kwon, Martin L. Moore, Sang-Moo Kang   +10 more
doaj   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A.   +24 more
core   +1 more source