Results 21 to 30 of about 109,215 (234)

Fractional-Fractal Modeling of Filtration-Consolidation Processes in Saline Saturated Soils

open access: yesFractal and Fractional, 2020
To study the peculiarities of anomalous consolidation processes in saturated porous (soil) media in the conditions of salt transfer, we present a new mathematical model developed on the base of the fractional-fractal approach that allows considering ...
Vsevolod Bohaienko, Volodymyr Bulavatsky
doaj   +1 more source

Vasculogenic mimicry score identifies the prognosis and immune landscape of lung adenocarcinoma

open access: yesFrontiers in Genetics, 2023
Background: Lung cancer has a high incidence and mortality rate worldwide. Vasculogenic mimicry (VM) is a specific modality of tumor angiogenesis that could potentially be a new target for tumor therapy.
Weichang Yang   +7 more
doaj   +1 more source

Exploring the potential reservoirs of Pseudomonas spp. bacteria at meat processing factories and poultry farms

open access: yesТеория и практика переработки мяса
One of the microorganisms that cause spoilage of meat during its storage is the bacteria Pseudomonas. To prevent contamination of the finished products with these bacteria, it is important to find the places at the enterprise where they aggregate. Within
D. S. Bataeva   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Post-castration variations in weight gain in a cohort of young adult male cats*

open access: yesJournal of Nutritional Science, 2014
The predisposition of cats to gain weight following neutering is well established; however, there is little information about the distribution and range of post-neutering weight gains observed in cats under a controlled environment.
Alfreda Wei   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Mathematical Modeling of Solutes Migration under the Conditions of Groundwater Filtration by the Model with the k-Caputo Fractional Derivative

open access: yesFractal and Fractional, 2018
Within the framework of a new mathematical model of convective diffusion with the k-Caputo derivative, we simulate the dynamics of anomalous soluble substances migration under the conditions of two-dimensional steady-state plane-vertical filtration with ...
Vsevolod Bohaienko, Volodymyr Bulavatsky
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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