Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. [PDF]
, 2013 While a number of genome-wide association studies have identified microtubule-associated protein tau as a strong risk factor for Parkinson's disease (PD), little is known about the mechanism through which human tau can predispose an individual to this ...
Chang, Hui-Yun +6 more
core +2 more sources
Frontiers in Oncology, 2021 PurposeEnhance rectum and bladder sparing in prostate SBRT with minimum increase in treatment time by complementing dual-arc coplanar VMAT with a two-beam non-coplanar IMRT class solution (CS).MethodsFor twenty patients, an optimizer for automated multi ...
Abdul Wahab M. Sharfo +5 more
doaj +1 more source
Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]
, 2009 Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Baur, Dorothee M. +8 more
core +2 more sources
Dosimetric Comparison of Three - Dimensional Conformal Radiation Therapy (3DCRT) and Posterior Partial Arc Volumetric Modulated Arc Therapy (VMAT) Plan for Craniospinal Irradiation [PDF]
Iranian Journal of Medical Physics, 2023 Introduction: This study compares three dimensional conformal radiotherapy (3DCRT) and Posterior Partial Arc volumetric modulated arc therapy (VMAT) planning techniques for treating craniospinal irradiation.
Neenu Tomy +3 more
doaj +1 more source
The Birmingham Boron Neutron Capture Therapy (BNCT) project : developments towards selective internal particle therapy [PDF]
, 2011 This paper will review progress on two aspects of the Birmingham BNCT project. Firstly on evaluation of the effects of high and low LET radiations when delivered simultaneously, and secondly on attempts to optimise delivery of the boron carrier compound ...
Boddy, A. +23 more
core +1 more source
A bi-objective optimization model for planning the treatment of cancer cells by volumetric modulated arc therapy [PDF]
مجله مدل سازی در مهندسی, 2021 Cancer, one of the leading causes of death in the world, has been on the rise in recent years and is expected to continue in the coming years. Therefore, the importance of developing a cancer control program and the need to provide effective methods is ...
Taha Keshavarz
doaj +1 more source
Feasibility of 3D tracking and adaptation of VMAT based on VMAT-CT
Radiotherapy and Oncology, 2020 Local computed tomography (CT) reconstruction is achievable with portal images acquired during volumetric-modulated arc therapy (VMAT) delivery and was named as VMAT-CT. However, the application of VMAT-CT is limited because it has limited field of view and no density information.
Xiaodong, Zhao, Rui, Zhang
openaire +3 more sources
Frontiers in Oncology, 2021 BackgroundAlthough there are some controversies regarding whole pelvic radiation therapy (WPRT) due to its gastrointestinal and hematologic toxicities, it is considered for patients with gynecological, rectal, and prostate cancer.
Hyunsoo Jang +16 more
doaj +1 more source
Lipid peroxidation and apoptotic response in rat brain areas induced by long-term administration of nandrolone: the mutual crosstalk between ROS and NF-kB [PDF]
, 2016 The aim of this study was to evaluate the played by oxidative stress in the apoptotic response in different brain areas of rats chronically treated with supra-physiological doses of nandrolone decanoate (ND).
Busardo', FRANCESCO PAOLO +9 more
core +2 more sources
Precision Radiation Oncology, 2021 Objective We aimed to compare the dosimetric characteristics of 6‐MV flattening filter mode (FF) and flattening filter‐free mode (FFF) volumetric‐modulated arc therapy (VMAT) plans in preoperative radiotherapy for rectal cancer using an Edge linear ...
Zhen Ding +5 more
doaj +1 more source