Results 151 to 160 of about 48,688 (308)

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge   +5 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

open access: yesAngewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet   +7 more
wiley   +2 more sources

Cardioprotection via vagus nerve stimulation preconditioning: Reducing ischaemia–reperfusion injury and arrhythmic risk

open access: yesExperimental Physiology, EarlyView.
Abstract Acute myocardial infarction is a leading cause of morbidity and mortality, with ischaemia–reperfusion (I/R) injury exacerbating myocardial damage. Vagus nerve stimulation (VNS) has been reported to exert cardioprotective effects, but its efficacy in preconditioning against I/R injury requires further investigation.
Feng Hu   +10 more
wiley   +1 more source

Pitfalls, benefits, and comparative analysis of artificial intelligence ChatBots in the systematic review process

open access: yesInternational Transactions in Operational Research, Volume 33, Issue 2, Page 719-774, March 2026.
Abstract The transformative potential of artificial intelligence (AI) ChatBots, leveraging natural language processing for information retrieval and knowledge synthesis, has garnered attention across diverse fields, including research. Recognizing AI's importance, researchers and policymakers are actively engaged in its development.
Cinzia Daraio   +2 more
wiley   +1 more source

Energy‐aware flexible job shop scheduling problem with nonlinear routes and position‐based learning effect

open access: yesInternational Transactions in Operational Research, Volume 33, Issue 2, Page 860-891, March 2026.
Abstract Sustainability has become one of the main objectives in all human activities and, in particular, in manufacturing environments. In this paper, we consider the flexible job shop scheduling problem with the objective of minimizing energy consumption.
Ernesto G. Birgin   +2 more
wiley   +1 more source

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