Results 211 to 220 of about 153,774 (304)

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Play to learn: innovating embryology education through a web-based gamification platform, and evaluating its effects on medical students' reaction, learning, and behavior. [PDF]

BMC Med Educ
Rahimipour M, Haghjoo R, Mosalanejad L, Karimian Z.   +3 more
europepmc   +1 more source

Evaluating Youth Participatory Action Research in the Americas: Comparative Insights on Empowerment, Methodologies, and Social Change

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Youth Participatory Action Research (YPAR) positions adolescents as co‐researchers to investigate and address social issues affecting their lives. While YPAR has gained global prominence, comparative research examining how it is conceptualized and practiced across regional contexts remains limited.
John Diaz, Paola Velasquez Quintero, Cody Gusto, Ivan Muñoz‐Echeverri, Camilo Norena Herrera, Laura Valencia   +5 more
wiley   +1 more source

Does a match-to-sample and physical prompting procedure result in receptive vocabulary learning in minimally speaking autistic preschoolers? [PDF]

Evid Based Commun Assess Interv
Edgar TC, Schabes CF, Mohammed L.
europepmc   +1 more source

Assessing cognition in autistic youth with and without attention‐deficit/hyperactivity disorder using the NIH Toolbox Cognition Battery: An Environmental influences on Child Health Outcomes‐Wide Cohort Study

JCPP Advances, EarlyView.
Autistic individuals tend to experience difficulties with fluid cognition as found previously, with minimal impact of ADHD. However, there was a notable proportion of autistic individuals with average or superior cognitive performance, highlighting the importance of strength‐based and transdiagnostic research approaches.
Catrina A. Calub, Aisha S. Dickerson, Haozuo Zhao, Robert M. Joseph, Michael O'Shea, Shaikh I. Ahmad, Lisa A. Croen, Sean C. L. Deoni, Viren A. D’Sa, Akhgar Ghassabian, Daphne Koinis‐Mitchell, Leonardo Trasande, Heather Volk, Anna J. Yeo, Irva Hertz‐Picciotto, Julie B. Schweitzer, Marjorie Solomon, for the ECHO Cohort Consortium   +17 more
wiley   +1 more source

Improving medical students' learning absorption in a knowledge graph based blended learning course. [PDF]

BMC Med Educ
Li B, Hu W, Duan A, Li Q, Li L, Li C, Weng C, Peng Z, Chen W, Li Y.   +9 more
europepmc   +1 more source

Mechanistic trials, therapy and developmental science—An exemplar from early autism care

JCPP Advances, EarlyView.
Abstract Background Mechanistic design and analysis in clinical trials remains relatively rare in child mental health and autism, despite the considerable value that it could have in developing therapy practice and in illuminating basic science. Clinical trials themselves continue to have insufficient influence on actual clinical practice in child ...
Jonathan Green
wiley   +1 more source

Opening New Worlds of Meaning-A Scoping Review of Figurative Language in Autism Spectrum Disorder. [PDF]

Behav Sci (Basel)
Skogli-Christensen B, Tyldum Lefstad K, Moufack MF, Chahboun S.   +3 more
europepmc   +1 more source

Teaching Occlusal Splints in the Digital Age: Comparing Student Experiences with Conventional and CAD/CAM Workflows

Journal of Dental Education, EarlyView.
ABSTRACT Background The teaching of occlusal splint therapy in dental education is evolving with the integration of digital workflows. Although digital tools offer operational advantages, conventional methods remain pedagogically relevant. Understanding students’ perceptions of both approaches is essential for guiding curriculum innovation.
Marcelo José Palma‐Fernandes, Júlio Ruiz‐Marrara, Maria Fernanda de Campos‐Muller, Melissa Oliveira de Melchior, Inês Sansonetty Gonçalves Côrte‐Real, Jardel Francisco Mazzi‐Chaves, Laís Valencise Magri   +6 more
wiley   +1 more source

The Cleveland Family Speech and Reading Study: A Review of Long-Term Outcomes Linking Phenotypes and Genotypes for Speech Sound Disorders. [PDF]

J Speech Lang Hear Res
Lewis BA, Miller GJ, Benchek P, Stein C, Iyengar SK.   +4 more
europepmc   +1 more source