Results 121 to 130 of about 75,980 (289)
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Max Weber: the vocation essays: "science as a vocation", "politics as a vocation"
, 2004 Originally published separately, Weber’s “Science as a Vocation” and “Politics as a Vocation” stand as the classic formulations of his positions on two related subjects that go to the heart of his thought: the nature and status of science and its claims ...
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The Vocation of Lay Catholics [PDF]
, 2009 Lay people who participate in the triple office of Christ and the Church realize their vocation by their presence and by being active in the world. The world and the requirements of life modify their Christian vocation in a particular way.
Kamiński, Ryszard
core
Vocation and Learning: A Popular Reading Course
, 1910 VOCATION AND LEARNING: A POPULAR READING COURSE Vocation and Learning: A Popular Reading Course (-
Münsterberg, Hugo
core +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
STRATEGY TO IMPROVE SAFETY ON CARGO SHIPS [PDF]
Russian Journal of Agricultural and Socio-Economic SciencesIn sea transportation, shipping safety is the main goal. In Indonesia, the safety of shipping for commercial vessels refers to national regulations, namely the Law of the Republic of Indonesia Number 17 of 2008 concerning Shipping and international ...
Kuncowati
doaj