Results 81 to 90 of about 75,931 (290)

Gender in the Teaching Profession: University Students' Views of Teaching as a Career

open access: yesCenter for Educational Policy Studies Journal, 2017
The purpose of our research is to gain a better insight into what encourages young adults, in particular young women, to enter the teaching profession.
Veronika Tašner   +2 more
doaj   +1 more source

Vocation For Boys

open access: yes, 1955
xi, 371 hal ...
STOVER, Edgar Morgan   +1 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

‘Missed Vocation? The Failed Writer in Late Victorian Women’s Fiction.’

open access: yes, 2014
The difficulties of self-presentation for Victorian women writers, and the troubled history of their literary standing, have been well documented. To take just one example, Helen Black’s Ladies Pictorial interviews with Notable Women Authors of the Day ...
Oulton, C.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IN SEARCH OF ITS OWN IDENTITY: MASS-MEDIA IN POST-COMMUNISM [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2014
The present research focuses on the mass-media system as it evolved in the first post-communist decade. Right after December 1989, hundreds of newspapers, magazines and other kinds of publications appeared in Romania.
Lucian CHIŞU
doaj  

Edukacyjne funkcje wolontariatu i ich percepcja w nauczaniu Kościoła w XXI wieku

open access: yesPaedagogia Christiana, 2014
Wzajemna pomoc międzyludzka jest elementem każdej cywilizacji i społeczeństwa, dlatego historia wolontariatu jest równie antyczna, jak istnienie rodzaju ludzkiego.
Piotr Krakowiak
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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