Results 61 to 70 of about 75,980 (289)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Organization, Technology and Management in Construction: An International Journal, 2018 The construction industry did not just evolve on its own. It is a product of the conscious efforts of several individuals called construction workers. In Nigeria, it is a large employer of the population, skilled, unskilled, and professional.
Odubiyi Tawakalitu Bisola
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2005 Biblical writers present a grand vision of the priestly vocation, in which the sacramental life of worship is translated into an ethical mission to the world.
Thomas B. Dozeman
core +1 more source
Vocation\u27s Unbroken Chain: Biblical Call Stories and the Experience of Vocation [PDF]
, 2020 This essay reflects on the Biblical passages used to create a vocational curriculum produced by the author\u27s doctoral project. The call stories of Abraham, Joseph, Moses, and Ruth are examined to illustrate the experience of vocation.
Keeton, Chris
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
HTS Teologiese Studies/Theological Studies, 2020 This article argues for a rediscovery of a theology of work in South Africa that is based on the Protestant notion of calling and vocation. Such a view has the primary intention of emphasising obedience and faithfulness to God rather than self-fulfilment
Dion A. Forster
doaj +1 more source
Vocational Students’ Ways of Handling the Academic/Vocational Divide
International Journal for Research in Vocational Education and Training, 2021 Purpose: The focus of this article is on Swedish vocational students’ own thoughts about different types of knowledge and how these thoughts relate to the forming of their vocational identities. The article reports on a study which investigates how vocational students handle the division between theoretical and practical knowledge as they learn to ...
openaire +6 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The Person and the Challenges, 2017 The article presents the basic principles of the spirituality of consecrated life as they are laid out in chapter VI of the Constitution on the Church. These principles can be summed up as the following: 1.
Mateusz Micek
doaj +1 more source