Results 61 to 70 of about 13,299 (265)

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley   +6 more
wiley   +1 more source

Reflecting on the nature of work in contemporary South Africa: A public theological engagement with calling and vocation

open access: yesHTS Teologiese Studies/Theological Studies, 2020
This article argues for a rediscovery of a theology of work in South Africa that is based on the Protestant notion of calling and vocation. Such a view has the primary intention of emphasising obedience and faithfulness to God rather than self-fulfilment
Dion A. Forster
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel   +36 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cervical mucus proteomics approach for swamp buffalo secreted fertility biomarker identification

open access: yesJournal of Veterinary Research
Reproductive efficiency in swamp buffalo (Bubalus bubalis) remains constrained by the lack of molecular tools to identify fertile females before service. The aim of this study was to discover biologically grounded biomarkers of fertility.
Yusuf Muhammad   +8 more
doaj   +1 more source

Die Grundzüge der Spiritualität des Ordenslebens im sechsten Kapitel in der dogmatischen Konstitution über die Kirche „Lumen gentium“

open access: yesThe Person and the Challenges, 2017
The article presents the basic principles of the spirituality of consecrated life as they are laid out in chapter VI of the Constitution on the Church. These principles can be summed up as the following: 1.
Mateusz Micek
doaj   +1 more source

Vocational Students’ Ways of Handling the Academic/Vocational Divide

open access: yesInternational Journal for Research in Vocational Education and Training, 2021
Purpose: The focus of this article is on Swedish vocational students’ own thoughts about different types of knowledge and how these thoughts relate to the forming of their vocational identities. The article reports on a study which investigates how vocational students handle the division between theoretical and practical knowledge as they learn to ...
openaire   +6 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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