Results 121 to 130 of about 13,530 (265)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

A new freshwater snail genus of Squamapicidae (Gastropoda, Truncatelloidea) with a novel posterior respiratory canal unveils an unexpected morphological innovation. [PDF]

Zookeys
Zheng H, Xing YH, Zhang LJ, Li Q, Chen ZG, Xiang HQ, Ouyang S, Huang XC, Wu XP.   +8 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Mental Health, Spirituality, and Flourishing in New Medical Residents. [PDF]

J Clin Med
Martínez-Sellés M, VanderWeele TJ.
europepmc   +1 more source

The Vocation—A Core Quality of Vocational Education and Training

Students often explain their choice of vocational education and training (VET) by their attraction to a specific vocation. They aspire to become a chef, a gardener or a carpenter and identify with the purpose and mean-ing associated with the vocation. And they want to acquire specific skills to produce goods and services val-ued by other people.
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The system and characteristics of teacher beliefs of preservice physical education teachers in China: a qualitative approach. [PDF]

Front Psychol
Li L.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Social inequalities in climate change concern and their relationship with health and wellbeing in adolescents, Barcelona 2021. [PDF]

J Clim Chang Health
Sánchez-Ledesma E, Ferrer-Fons M, Serral G, López-Muley C, Santiá P, Pérez K, López MJ, Oliveras L.   +7 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source