Results 101 to 110 of about 75,931 (290)
Summer religious vocation school, 1938
, 1938 Elementary school boys and Jesuit participants in summer religious vocation school<br>Verso caption: Vocation School, 1938 Student group photos, mixed ages, 1931 ...
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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Eminescology – a Constant Concern of the Researcher Dumitru Apetri
PhilologiaThe article reveals the contribution of the scholar and writer Dumitru Apetri to Eminescian creation and Eminescology – masterful fields of Romanian philology.
Vlad CARAMAN
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Boundaries and Relationships in Homelessness Work: Lola, an Agency Manager
Forum: Qualitative Social Research, 2004 The professional is also a human being. This paper explores the complementary and contradictory relation between biography and vocation in the history of a nurse who became a social work manager, as revealed in a biographic-narrative interview.
Tom Wengraf
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Hohol’s Anthropological Project in the Russian Empire
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen'Purpose. To reconstruct Hohol’s point of view on his anthropological project, that is, to identify his answers to the question of what a person is in the dimensions of the essential and the proper.
A. M. Malivskyi +2 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
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Vocational Rehabilitation [PDF]
Journal of the Royal Society of Medicine, 2003 Andrew O, Frank, Philip, Sawney
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source