Results 201 to 210 of about 19,959,634 (288)

Laryngeal dystonia: a comprehensive review of aetiology, clinical presentation, diagnosis, and treatment approaches. [PDF]

open access: yesEur Arch Otorhinolaryngol
Ionescu MT   +7 more
europepmc   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai   +13 more
wiley   +1 more source

Architecting Anisotropic Force‐Responsive Bidirectional High‐Contrast Three‐Color Fluorescence Switches via Effective Molecular Modulation for High‐Security Information Storage

open access: yesAdvanced Science, EarlyView.
Synergistically integrating substituent variation and positional isomerism in molecular engineering affords 13 rare tricolored mechanofluorochromic luminogens, and 3 exceedingly scarce force‐triggered bidirectional high‐contrast three‐color fluorescence switches are screened out via a three‐step protocol.
Yijie Zou   +7 more
wiley   +1 more source

To Be or Not to Be Eutectic: Anomalous Glass Forming Ability Governed by Melt Structural Complexity

open access: yesAdvanced Science, EarlyView.
Challenging the eutectic rule, congruently melting Ti–Cu alloys show greater glass‐forming ability than their eutectic counterparts. This arises from the congruent melt's structural complexity: higher cluster diversity and stronger inter‐cluster correlations from entropy–enthalpy competition.
Wei Chen   +18 more
wiley   +1 more source

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

open access: yesAdvanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu   +16 more
wiley   +1 more source

Voice-Based Screening of Depression and Anxiety Using Machine Learning and Deep Learning: A Scoping Review of Methods and Clinical Readiness. [PDF]

open access: yesLife (Basel)
Muntean-Codrea M   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy