Results 211 to 220 of about 19,959,634 (288)

An Explainable Multimodal Deep‐Learning Model Using Histopathological Image and Clinical Information for Prognosis Prediction in Colorectal Cancer: A Multi‐Center Cohort Study

open access: yesAdvanced Science, EarlyView.
This study develops a multimodal deep‐learning model that integrates clinical variables and histopathological images to predict survival outcomes in colorectal cancer. The multimodal model effectively stratifies patients into low‐ and high‐risk groups, demonstrating superior accuracy and generalizability across multiple independent cohorts.
Zhihan Jiang   +12 more
wiley   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

open access: yesAdvanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li   +14 more
wiley   +1 more source

Gradient‐Oxidized Bacterial Cellulose for Self‐Sustained Soil Moisture Sensing

open access: yesAdvanced Science, EarlyView.
An asymmetric encapsulated bacterial cellulose device integrates a gradient‐oxidized BC framework with a LiCl‐doped Ecoflex hygroscopic layer, enabling self‐powered soil moisture monitoring through directional ion transport. The device sustains stable hydrovoltaic output, supports deep‐learning humidity classification, and fully biodegrades in soil ...
Nan Zhou   +10 more
wiley   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

open access: yesAdvanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau   +3 more
wiley   +1 more source

PVminerLLM: structured extraction of patient voice from patient-generated text using large language models. [PDF]

open access: yesNPJ Digit Public Health
Jamal Fodeh S   +7 more
europepmc   +1 more source

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