Results 101 to 110 of about 313,264 (302)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

The Impact of Laser Irradiation on Thin ZrN Films Deposited by Pulsed DC Magnetron Sputtering

Nanomaterials
Transition metal nitrides have extensive applications, including magnetic storage devices, hardware resistance coatings, and low-temperature fuel cells.
Ameena Nazneen, Penghui Lei, Di Yun
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Investigation of the hydraulic characteristics and homogeneity of the microstructure of the air voids in the sustainable rigid pavement

Open Engineering
The present research investigates how incorporating waste concrete block aggregates (WCBA) in place of natural coarse (5–12 mm) aggregates (NCA) affect the characteristics of concrete pavement. The topography of the voids, water absorption, porosity, and
Maarij Zainab S., Saadoon Tahseen D., Hasan Maan S., Dulaimi Anmar   +3 more
doaj   +1 more source

Morphologies of galaxies within voids [PDF]

A&A 692, A258 (2024)
In this work we investigate the effects of the environment on the evolution of void galaxies. In particular, we study their morphology and explore its dependence with their location within the void where the galaxies reside, as well as with properties of the void, such as void size or galaxy number-density.
arxiv   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Characterization of Air Voids Distribution in the Open-Graded Asphalt Mixture Based on 2D Image Analysis

Applied Sciences, 2019
The air voids distribution has a significant effect on the pavement performance related distresses such as rutting, cracking, moisture damage and permeability.
Guangji Xu, Xiao Chen, Xiaoming Huang, Tao Ma, Wei Zhou   +4 more
doaj   +1 more source

Properties of voids in the Local Volume

, 2007
Current explanation of the overabundance of dark matter subhalos in the Local Group (LG) indicates that there maybe a limit on mass of a halo, which can host a galaxy.
A. Dekel, A.V. Kravtsov, A.V. Kravtsov, A.V. Tikhonov, I.D. Karachentsev, P.J.E. Peebles, S. Gottlöber, S.G. Patiri   +7 more
core   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Precision cosmography with stacked voids

, 2012
We present a purely geometrical method for probing the expansion history of the Universe from the observation of the shape of stacked voids in spectroscopic redshift surveys.
Abazajian, Albrecht, Ballinger, Benjamin D. Wandelt, Blanton, Cool, Guilhem Lavaux, Hoyle, Ilbert, Jasche, Jimenez, Jones, Kochanek, Komatsu, Kowalski, Laureijs, Lewis, Park, Schlegel, Schmidt, van de Weygaert   +20 more
core   +2 more sources