Results 91 to 100 of about 19,426 (298)

Intravenous application of a primary sevoflurane metabolite improves outcome in murine septic peritonitis: first results.

PLoS ONE, 2013
Volatile anesthetics are known to have immunomodulatory effects in conditions of organ injury. A recent study in an experimental sepsis model has shown remarkably improved survival when mice were exposed to volatile anesthetics.
Inge K Herrmann, Maricela Castellon, David E Schwartz, Melanie Hasler, Martin Urner, Guochang Hu, Richard D Minshall, Beatrice Beck-Schimmer   +7 more
doaj   +1 more source

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]

, 2018
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl, Carnevale, Vincenzo, Covarrubias, Manuel, Dailey, William P., Eckenhoff, Roderic G., Granata, Daniele, Klein, Michael L., Tang, Pei, Wang, Yali, Wells, Marta M., Woll, Kellie, Xu, Yan, Yang, Elaine   +12 more
core   +1 more source

A noninvasive monitoring device for anesthetics in fish [PDF]

, 2010
A noninvasive device capable of recording both gill and lateral fin movements was assembled and used to analyze initial and post-treatment activity frequency (Hz) in fish exposed to anesthetics.
Fuentes, J., Harrison, Adrian P., Power, Deborah   +2 more
core   +2 more sources

Ischemia-Reperfusion Injury and Volatile Anesthetics [PDF]

BioMed Research International, 2014
Ischemia-reperfusion injury (IRI) is induced as a result of reentry of the blood and oxygen to ischemic tissue. Antioxidant and some other drugs have protective effect on IRI. In many surgeries and clinical conditions IRI is counteract inevitable. Some anesthetic agents may have a protective role in this procedure.
openaire   +2 more sources

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh, Alhasan Altayf, Ayham Qatza, Abubaker Alghazal, Hasan Al‐sakkaf, Muhammed Elhadi   +5 more
wiley   +1 more source

Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation [PDF]

, 2018
Propofol is widely used in the clinic for the induction and maintenance of general anesthesia. As with most general anesthetics, however, our understanding of its mechanism of action remains incomplete.
Carnevale, Vincenzo, Covarrubias, Manuel, Eckenhoff, Roderic G., Granata, Daniele, Yang, Elaine   +4 more
core   +1 more source

On the action potential as a propagating density pulse and the role of anesthetics [PDF]

, 2006
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings on nerves that are not contained in this classical theory.
ANDREW D. JACKSON, Campagna J. A., Hodgkin A. L., Kharakoz D. P., Kobatake Y., Meyer H., Neher E., Ostwald W., Overton C. E., Overton C. E., Petrov A. G., Ritchie J. M., THOMAS HEIMBURG, Träuble H.   +13 more
core   +2 more sources

A walk in the park—Identifying healthy greenspaces using scents

PLANTS, PEOPLE, PLANET, EarlyView.
As urbanisation accelerates globally, access to nature is increasingly recognised as vital for public health and wellbeing. We captured and analysed plant‐emitted airborne ‘scent signatures’ across Oxford's urban greenspaces to assess their potential health relevance.
William T. Kay, Anya Lindström Battle, Mahal Humberstone, Molly Tucker, Kieran E. Storer, Geoffrey Kite, Katherine Willis   +6 more
wiley   +1 more source

Conned by the enemy: the entomopathogenic fungus Metarhizium anisopliae lures and kills Drosophila suzukii

Pest Management Science, EarlyView.
Highly pathogenic isolates of Metarhizium anisopliae attracted Drosophila suzukii. Identifying the responsible compounds for this attraction could help the development of these isolates for pest monitoring and overall pest management. Abstract BACKGROUND Drosophila suzukii, commonly known as spotted wing drosophila (SWD), is a highly invasive and ...
Ibrahim M Farid, Shepard Ndlela, Paul G Becher, Christopher W Weldon, Abdelmutalab GA Azrag, Helgi B Schiöth, Samira A Mohamed, Sunday Ekesi   +7 more
wiley   +1 more source

Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence

Journal of Translational Medicine, 2018
Background The relationship between surgery and anesthetic-induced immunosuppression and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system (SNS) to cause ...
Ryungsa Kim
doaj   +1 more source