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Volatile anesthetic-induced cardiac preconditioning
Journal of Anesthesia, 2007Pharmacological preconditioning with volatile anesthetics, or anesthetic-induced preconditioning (APC), is a phenomenon whereby a brief exposure to volatile anesthetic agents protects the heart from the potentially fatal consequences of a subsequent prolonged period of myocardial ischemia and reperfusion.
Stadnicka, Anna +4 more
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Volatile Anesthetics and Cardiac Function
Seminars in Cardiothoracic and Vascular Anesthesia, 2006All volatile anesthetics have been shown to induce a dose-dependent decrease in myocardial contractility and cardiac loading conditions. These depressant effects decrease myocardial oxygen demand and may, therefore, have a beneficial role on the myocardial oxygen balance during myocardial ischemia.
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Der Anaesthesist, 2004
None of the currently available inhaled anesthetics has all of the properties of an "ideal" inhaled agent. The exceptionally low solubility of desflurane and sevoflurane offers a significantly greater precision of control over maintenance of anesthesia and a potential for a more rapid recovery from anesthesia than other inhaled anesthetics. Sevoflurane
M, Loscar, P, Conzen
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None of the currently available inhaled anesthetics has all of the properties of an "ideal" inhaled agent. The exceptionally low solubility of desflurane and sevoflurane offers a significantly greater precision of control over maintenance of anesthesia and a potential for a more rapid recovery from anesthesia than other inhaled anesthetics. Sevoflurane
M, Loscar, P, Conzen
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Drug Interactions: Volatile Anesthetics and Opioids
Journal of Clinical Anesthesia, 1997Multiple drugs are used to provide anesthesia. Volatile anesthetics are commonly combined with opioids. Several studies have demonstrated that small doses of opioid (i.e., within the analgesic range) result in a marked reduction in minimum alveolar concentration (MAC) of the volatile anesthetic that will prevent purposeful movement in 50% of patients ...
P S, Glass +3 more
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Volatile Anesthetics Depress Spinal Motor Neurons
Anesthesiology, 1996Background Depression of spinal alpha-motor neurons apparently plays a role in the surgical immobility induced by isoflurane. Using the noninvasive technique of F-wave analysis, the authors tested the hypothesis that depressed motor neuron excitability is an effect common to other clinically relevant inhaled anesthetics.
I J, Rampil, B S, King
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Volatile Anesthetics and Neuroprotection
2015Since 1963, many studies have demonstrated the protective and preconditioning effects of volatile anesthetics on cerebral ischemia, and it has also been suggested that they can delay neuronal cell death, especially in the developing brain. Various molecular mechanisms involving the numerous pathways of the neuronal cell death cascade have been reported
Yasunori Mishima, Kazuo Ushijima
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Volatile anesthetic effects on ischemic myocardium
Current Opinion in Anaesthesiology, 1998Volatile anesthetics, particularly the new generation of agents, have a very rapid onset and offset of action. These properties allow for quick recovery from clinical anesthesia. Because there is additional evidence that these agents have protective effects during myocardial ischemia, there may be advantages for 'fast tracking' patients undergoing ...
N, Nader-Djalal, P R, Knight
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Anesthesiology Clinics of North America, 1993
Summary In conclusion, the physiologic response to desflurane, for the most part, closely mimics the response to isoflurane. In the steady state, it is difficult to distinguish these two drugs on the basis of their effect on the central and regional hemodynamics, as well as on pulmonary function.
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Summary In conclusion, the physiologic response to desflurane, for the most part, closely mimics the response to isoflurane. In the steady state, it is difficult to distinguish these two drugs on the basis of their effect on the central and regional hemodynamics, as well as on pulmonary function.
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Volatile anesthetics and mucociliary clearance.
Minerva anestesiologica, 2008The aim of this prospective, randomized, double blind study was to evaluate the possible modification of in vivo nasal mucociliary clearance by three different volatile agents: sevoflurane, isoflurane and desflurane, following intravenous induction and tracheal intubation.Following institutional approval and informed consent, 60 patients scheduled for ...
Kutluhan, AHMET +5 more
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Volatile Anesthetics Reduce Mortality in Cardiac Surgery
Journal of Cardiothoracic and Vascular Anesthesia, 2009A recent meta-analysis suggested that volatile anesthetics reduce postoperative mortality after cardiac surgery. Nonetheless, whether volatile anesthetics improve the outcome of cardiac surgical patients is still a matter of debate. The authors investigated whether the use of volatile anesthetics reduces mortality in cardiac surgery.
BIGNAMI E +7 more
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