Results 41 to 50 of about 927 (261)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

A Review of Paleo El Niño-Southern Oscillation

open access: yesAtmosphere, 2018
The Earth has seen El Niño-Southern Oscillation (ENSO)—the leading mode of interannual climate variability—for at least millennia and likely over millions of years.
Zhengyao Lu   +3 more
doaj   +1 more source

Impact of global warming on the rise of volcanic plumes and implications for future volcanic aerosol forcing [PDF]

open access: yesJournal of Geophysical Research: Atmospheres, 2016
AbstractVolcanic eruptions have a significant impact on climate when they inject sulfur gases into the stratosphere. The dynamics of eruption plumes is also affected by climate itself, as atmospheric stratification impacts plumes' height. We use an integral plume model to assess changes in volcanic plume maximum rise heights as a consequence of global ...
Thomas J. Aubry   +6 more
openaire   +3 more sources

Graphene Quantum Dot‐Induced Microstrain for Framework Stabilization of High‐Entropy Prussian Blue Analog in High‐Current Alkaline Hydrogen Evolution Reaction

open access: yesAdvanced Functional Materials, EarlyView.
The intrinsic distortion‐rich lattice of HEPBA with GQD‐enabled microstrain engineering establishes a mechanistic route toward high‐performance alkaline hydrogen evolution reaction. HEPBA inherently feature heterogeneous local coordination environments arising from multimetal incorporation, while properly introducing GQD during coprecipitation ...
Mia Rinawati   +10 more
wiley   +1 more source

Clarifying the Relative Role of Forcing Uncertainties and Initial‐Condition Unknowns in Spreading the Climate Response to Volcanic Eruptions

open access: yesGeophysical Research Letters, 2019
Radiative forcing from volcanic aerosol impacts surface temperatures; however, the background climate state also affects the response. A key question thus concerns whether constraining forcing estimates is more important than constraining initial ...
Davide Zanchettin   +6 more
doaj   +1 more source

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

open access: yesAdvanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang   +13 more
wiley   +1 more source

Revisiting the Agung 1963 volcanic forcing – impact of one or two eruptions [PDF]

open access: yesAtmospheric Chemistry and Physics, 2019
Abstract. In 1963 a series of eruptions of Mt. Agung, Indonesia, resulted in the 3rd largest eruption of the 20th century and claimed about 1900 lives. Two eruptions of this series injected SO2 into the stratosphere, a requirement to get a long lasting stratospheric sulfate layer.
Ulrike Niemeier   +2 more
openaire   +5 more sources

Functionalizing Micro‐to‐Mesoscopic Electrode Architectures for Regulating Electron Transfer Behaviors in Electrocatalysis

open access: yesAdvanced Functional Materials, EarlyView.
A systematic review is conducted to assess the influence of electrode architecture across micro‐ to mesoscopic length scales on electron‐transfer pathways in electrocatalysis. We discuss the structure‐activity relationships in electrocatalytic applications, including resource recovery and environmental remediation, and provide cost‐effective, efficient
Manshu Zhao   +6 more
wiley   +1 more source

Evidence for volcanic forcing of Holocene cold events

open access: yesNature Communications
Abstract During the Holocene, the climatic stability of the northern hemisphere was intermittently disrupted by centennial-scale cooling events, whose origins remain unclear. Explosive volcanism is a plausible trigger, yet its potential to drive longer-term (centennial-to-millennial) perturbations remains underexplored.
Alice R. Paine   +5 more
openaire   +1 more source

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