Results 101 to 110 of about 623,919 (404)

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Formation and distribution of volcanic hydrocarbon reservoirs in sedimentary basins of China

Petroleum Exploration and Development, 2008
Volcanic hydrocarbon exploration in China has experienced three phases: accidental discovery, local prospecting, and all-round exploration. There are mainly Carboniferous-Permian, Jurassic-Cretaceous, Paleogene-Neogene volcanic rocks and lava ...
Cai-neng ZOU, Wen-zhi ZHAO, Cheng-zao JIA, Ru-kai ZHU, Guang-ya ZHANG, Xia ZHAO, Xuan-jun YUAN   +6 more
doaj   +1 more source

Nature and origin of secondary mineral coatings on volcanic rocks of the Black Mountain, Stonewall Mountain, and Kane Springs Wash volcanic centers, southern, Nevada [PDF]

The following subject areas are covered: (1) genetic, spectral, and LANDSAT Thematic Mapper imagery relationship between desert varnish and tertiary volcanic host rocks, southern Nevada; (2) reconnaissance geologic mapping of the Kane Springs Wash ...
Chenevey, Michael J., Hsu, Liang C., Spatz, David M., Taranik, James V.   +3 more
core   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Sr-Nd isotope geochemistry of the early Precambrian sub-alkaline mafic igneous rocks from the southern Bastar craton, Central India [PDF]

, 2009
Sr–Nd isotope data are reported for the early Precambrian sub-alkaline mafic igneous rocks of the southern Bastar craton, central India. These mafic rocks are mostly dykes but there are a few volcanic exposures.
BL Weaver, DA Papanastassiou, DJ DePaolo, F Kalsbeek, G Sarkar, Gulab C. Gautam, H Crookshank, HC Halls, J Blichert-Toft, JE French, JE French, JJW Rogers, JJW Rogers, M Anand, M Ramakrishnan, NM Evensen, Rajesh K. Srivastava, RCO Gill, RE Ernst, RE Ernst, RK Srivastava, RK Srivastava, RK Srivastava, RK Srivastava, RK Srivastava, RK Srivastava, RK Srivastava, RK Srivastava, RK Srivastava, RL Rudnick, Rob M. Ellam, RP Hall, RW Maitre Le, SA Drury, SL Goldstein, SM Naqvi, SR Taylor, TE Krough, TN Irvine, V Rajamani   +39 more
core   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Complex examination of the Upper Paleozoic siliciclastic rocks from southern Transdanubia, SW Hungary—Mineralogical, petrographic, and geochemical study [PDF]

, 2007
A vertical section of Upper Paleozoic sandstones from southern Transdanubia (Mecsek-Villány area, Tisza mega-unit, Hungary) has been analyzed for major and trace elements, including rare earth elements (REEs).
Á, Arribas, Awdankiewicz, Balogh, Bauluz, Bhatia, Bhatia, Biscaye, Brü, Cox, Csontos, Csontos, Csontos, Cullers, Cullers, Fazekas, Fedo, Gaillardet, Garver, Golonka, Haas, Huang, Kü, Lee, Nagy, Nesbitt, Noda, Pearce, Preston, Varga, Varga, Varga, Varga, Watanabe, Willan, Zimmermann   +35 more
core   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

Dating and source determination of volcanic rocks from Khunik area (South of Birjand, South Khorasan) using Rb-Sr and Sm-Nd isotopes [PDF]

پترولوژی, 2016
The Khunik area is located in the south of Birjand, Khorasan province, in the eastern margin of Lut block. Tertiary volcanic rocks have andesite to trachy-andesite composition.
Somayeh Samiee, Mohammad Hassan Karimpour, Majid Ghaderi, Mohammad Reza Hidarian Shahri, Jose Francisco Santos   +4 more
doaj