Results 41 to 50 of about 1,019,029 (303)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Improving the performance of grid‐connected inverters during asymmetrical faults and unbalanced grid voltages

IET Generation, Transmission & Distribution
The increasing penetration of the distributed energy resources (DER) in the power grid, which, while having significant advantages, also pose significant challenges.
Sepideh Shabani, Mehdi Gholipour, Mehdi Niroomand   +2 more
doaj   +1 more source

Examination on the parameter stability region of the VSC control system in VSC-HVDC transmission systems

The Journal of Engineering, 2019
Nowadays, the voltage source converter (VSC)-based high-voltage direct current (HVDC) transmission technology is widely adopted for the integration of renewable power generations.
Long Xu, Guoyun Su, Wenjuan Du, Chen Chen, Bixing Ren, Haifeng Wang   +5 more
doaj   +1 more source

Active arc suppression device based on voltage‐source convertor with consideration of line impedance in distribution networks [PDF]

, 2021
Bishuang Fan, Haihang Ma, Wen Wang, Ganzhou Yao, Qikai Li, Xiangjun Zeng, Josep M. Guerrero   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Multi-hierarchy control strategy in abc coordinate for modular multilevel matrix converter in fractional frequency transmission system

The Journal of Engineering, 2019
This paper proposes a multi-hierarchy control strategy in abc coordinate for modular multilevel matrix converter (M^3C) in fractional frequency transmission system (FFTS).
Zhujian Ou, Guangzhu Wang
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A multi‐power quality problems management strategy based on VSCs and switches in AC/DC hybrid LVDN with large PVs

IET Renewable Power Generation
A large scale of distributed photovoltaics is accessed through a low voltage distribution network in a single‐phase or two‐phase, which causes three‐phase unbalance and over‐voltage problems.
Yu Fu, Weichen Yang, Yue Li, Hao Bai, Yongxiang Cai, Wei Li   +5 more
doaj   +1 more source

Pilot protection scheme for transmission line of a hybrid HVDC system based on polarity characteristics of current and voltage fault components

The Journal of Engineering, 2019
A hybrid high-voltage direct current (HVDC) system comprises a line commutated converter (LCC) at the rectifier side and a voltage source converter (VSC) at the inverter side, combining advantages of both LCC and VSC systems.
Yanting Wang, Baohui Zhang, Baohui Zhang, Shaojie Cheng   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source