Results 61 to 70 of about 2,781 (260)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Stirling Convertor Controller Development at NASA Glenn Research Center [PDF]

open access: yes
For nearly two decades, NASA Glenn Research Center has been supporting the development of radioisotope power systems (RPS). NASA desires higher conversion efficiency RPS options that are reliable and robust with long-life design. Dynamic conversion, such
Dugala, Gina M.
core   +4 more sources

Evaluation of DC-link voltage ripple in five-phase PWM voltage source inverters

open access: yesThe Journal of Engineering, 2019
This paper presents the analysis of the DC-link voltage switching ripple in five-phase PWM voltage source inverters with balanced load. The analysis is particularly important for the design and selection of a DC-link capacitor making it possible to meet ...
M. Vujacic   +4 more
doaj   +1 more source

NASA Proof-of-Concept 1-W(sub e) Stirling Convertor Development for Small Radioisotope Power Systems [PDF]

open access: yes
Low power Stirling convertors are being developed at NASA Glenn Research Center to provide future small spacecraft with electrical power by converting heat from one or more Light Weight Radioisotope Heater Units (LWRHU).
Casciani, Michael R.   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Small power ZVS circuits for the marine-controlled source electromagnetic transmitter

open access: yesThe Journal of Engineering, 2019
Marine-controlled source electromagnetic transmitter is an important equipment for the investigation of marine geology and exploration of oil, gas, and mineral resources in recent years.
Hongxi Song   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A second‐order sliding mode control with active disturbance rejection for dynamic voltage restorers

open access: yesIET Power Electronics
This paper proposes an extended state observer (ESO)‐based second‐order sliding mode control (SMC) for dynamic voltage restorers (DVRs). Unlike the conventional first‐order SMC and some second‐order SMC (SOSMC) methods that suffer from chattering, the ...
Farzaneh Bagheri   +3 more
doaj   +1 more source

Solution to reduce voltage stress of sub-module in LCC–MMC transmission system at the condition of communication fault

open access: yesThe Journal of Engineering, 2018
Line commutate converter–modular multilevel converter (LCC–MMC) hybrid high voltage direct current (HVDC) system combines the advantages of both LCC-HVDC and MMC-HVDC, and will be wildly used in the future.
Dengjiang Xing   +8 more
doaj   +1 more source

Directional derivative-based method for quasi-stationary voltage support analysis of single-infeed VSC-HVDC units

open access: yesHigh Voltage, 2020
This study presents an investigation of the impact of the quasi-stationary voltage support provided by a voltage source converter (VSC) connected to a single point of a power system.
Arcadio Perilla   +9 more
doaj   +1 more source

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